Recent evidence has demonstrated that inquiry-based physiology laboratories improve students' critical- and analytical-thinking skills. We implemented inquiry-based learning into three physiology courses: Comparative Vertebrate Physiology (majors), Human Physiology (majors), and Human Anatomy and Physiology (nonmajors). The aims of our curricular modifications were to improve the teaching of ph...

Lotte Leick, Ylva Hellsten, Joachim Fentz, Stine S. Lyngby, Jørgen F. P. Wojtaszewski, Juan Hidalgo, and Henriette Pilegaard Centre of Inflammation and Metabolism and Copenhagen Muscle Research Centre, Department of Biology, Section of Molecular, Cellular, and Integrative Physiology; Copenhagen Muscle Research Centre, Molecular Physiology Group, Section of Human Physiology, Department of Exerci...

Robert F. Chapman, Abigail S. Laymon Stickford, Carsten Lundby, and Benjamin D. Levine Human Performance Laboratory, Department of Kinesiology, Indiana University, Bloomington, Indiana; Center for Integrative Human Physiology, Institute of Physiology, University of Zurich, Switzerland; and Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas and University of Texas...

A13 Interactions of peripheral and central μ opioid systems during emotional stress Valentina Bashkatova, Helmut Prast, Alexei Umriukhin and Sergey Sudakov Department of Reinforcement Physiology, P.K. Anokhin Research Institute of Normal Physiology RAMS, 125315 Moscow, Russia Department of Pharmacology and Toxicology, University of Innsbruck, 6020 Innsbruck, Austria Department of Addictive Phys...

Leptin, discovered through positional cloning 15 years ago, is an adipocyte-secreted hormone with pleiotropic effects in the physiology and pathophysiology of energy homeostasis, endocrinology, and metabolism. Studies in vitro and in animal models highlight the potential for leptin to regulate a number of physiological functions. Available evidence from human studies indicates that leptin has a...

Of the two variants of adipose tissue, white fat is traditionally known as a lipid rich tissue which undergoes pathological expansion in obese conditions. To counter the excess accumulation of white fat in states of energy imbalance, the second and unique type of brown fat plays a key role by burning extra energy into heat through a special metabolic pathway. In addition brown fat also plays a ...

Adipose tissue is now recognised as a highly active metabolic and endocrine organ. Great strides have been made in uncovering the multiple functions of the adipocyte in cellular and molecular detail, but it is essential to remember that adipose tissue normally operates as a structured whole. Its functions are regulated by multiple external influences such as autonomic nervous system activity, t...

This well-established textbook , now in its Third edition, provides an attractive, authorative and integrated review of organ function and systems interactions in the normal body. The authors have two particular aims – to emphasise cellular physiology and to discuss the relevance of normal function to disturbed organ function or patho-physiology. The clear diagrams and coherent text will attrac...

The paper discusses the biochemical and physiological significance of magnesium. Also, attention is paid to the development of lesions related to magnesium deficiency.

Over the past five years, the importance of a diverse class of 18-24 nucleotide RNA molecules, known as microRNAs (miRNAs) has increasingly been recognized. These highly conserved RNAs regulate the stability and translational efficiency of complementary target messenger RNAs. The human genome is now predicted to encode nearly 1,000 miRNAs that likely regulate at least one third of all human tra...