نتایج جستجو برای: homozygous sickle cell disease

تعداد نتایج: 2943221  

Journal: :Annals of International medical and Dental Research 2017

2014
Karishma Singh

Background: The inherited disorders of haemoglobin are the commonest single gene disorder of the world population. Sickle cell anaemia being the most widespread and numerically the most important haemoglobinopathy in the world today. The major features of sickle cell disease (SCD) in most patients are lifelong anaemia and the consequences of recurrent vaso-occlusion. Many complications of SCD i...

Background: Until now, trimodal distribution of HbS has been seen by six different studies in the world when associated with alpha-thalassemia with confirmation by corresponding alpha-genotyping studies. The RBC indices reduce as alpha-globin genes reduce in sickle cell trait (SCT) patients, which decreases the extent of intra-vascular sickling and thus betters the clinical cou...

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