La lesión pulmonar aguda producida por transfusión (TRALI) es un síndrome grave y potencialmente mortal. FDA ha informado que TRALI la principal causa muertes relacionadas con transfusiones durante muchos años, el 34% de las víctimas mortales (64/186 reportaron entre 2012 2016). asociación antígeno humano neutrófilos (HNA) o leucocitario (HLA) se encuentran en los anticuerpos sangre donantes as...

Background: Improving the quality of health care services requires tailoring facilities to fulfil patients' needs. Satisfying patients' healthcare needs, listening to patients' opinions and building a closer provider-user partnership are central to the NHS. Few published studies have discussed cardiovascular patients' health needs, but they are not comprehensive and fail to explore the contribu...

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Puckering of the sugar unit in nucleosides and nucleotides is an important structural aspect that directly influences helical structure nucleic acids. The preference for specific puckering modes acids can be analyzed via silico conformational analysis, but large amount conformations accuracy analysis leads to extensive computational time. In this paper, we show combination geometry optimization...

The combined use of surface plasmon resonance (SPR) and modified or mimic oligonucleotides have expanded diagnostic capabilities of SPR-based biosensors and have allowed detailed studies of molecular recognition processes. This review summarizes the most significant advances made in this area over the past 15 years.   Functional and conformationally restricted DNA analogs (e.g., aptamers an...

Organism size reduction with increasing temperature has been suggested as a universal response to global warming. Since genome size is usually correlated to cell size, reduction of genome size in unicells could be a parallel outcome of warming at ecological and evolutionary time scales. In this study, the short-term response of cell size and nucleic acid content of coastal marine prokaryotic co...

BACKGROUND Chronic inflammation accompanied by arginine deficiency, immune dysfunction, and excess nitric oxide (NO) production is a clinical condition found in patients with peritonitis. A previous study showed that the nonselective NOS inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME) may facilitate the metabolism of the immune nutrient arginine without altering NO homeostasis in rats wit...

BACKGROUND Congenital long-QT syndrome (LQTS) is a primary arrhythmogenic syndrome stemming from perturbed cardiac repolarization. LQTS, which affects approximately 1 in 3000 persons, is 1 of the most common causes of autopsy-negative sudden death in the young. Since the sentinel discovery of cardiac channel gene mutations in LQTS in 1995, hundreds of mutations in 8 LQTS susceptibility genes ha...

Tujuan penelitian ini untuk mengetahui, menganalisa, dan memberikan bukti empiris Kualitas Pelayanan, Produk, Harga Sebagai Penentu Kepuasan Konsumen Toko Online HNA Shop. Penelitian menggunakan metode pengambilan data primer yaitu dengan menyebar kuisioner populasi konsumen Pengambilan sampel teknik simpel random sampling berjumlah 100 responden. Teknik analisa yang digunakan uji : validitas, ...