Thiazolidinediones (TZDs) improve glycemic control and insulin sensitivity in patients with type 2 diabetes mellitus (T2DM). There is growing evidence from in vivo and in vitro studies that TZDs improve pancreatic beta-cell function. The aim of this study was to determine whether TZD-induced improvement in glycemic control is associated with improved beta-cell function. We studied 11 normal glu...

The routine measurement of hemoglobin A1c (Hb A1c) 1 has become an essential component of the standard of care for patients with diabetes and has been recommended by major clinical diabetes organizations. A small amount of evidence shows that having the Hb A1c result at the time of the doctor’s visit is beneficial (1 ). Recently, there has been discussion about whether the quality of point-ofca...

Background: Anemia may be considered to be an independent risk factor for the development of diabetic retinopathy (DR) in patients with renal failure. The purpose of this study was to investigate the association between blood hemoglobin level and retinopathy in diabetic patients with normal renal function tests.Methods: From 2009 to 2011, 1100 diabetic patients underwent retinal examination. Am...

objective: suicide is seen in major depression, also in chronic diseases patients. hba1c is a marker of long-term control of diabetes. the aim of this study was evaluation of the suicidal ideations in diabetic patients and its association with the status of blood sugar control based on hemoglobin a1c (hb a1c). materials and methods: this study is a cross-sectional study. the patients were selec...

Sir, HbA1c testing is mainly used for monitoring glycaemic control in patients with diabetes. However, the World Health Organization now recommends that HbA1c can be used as a diagnostic test for diabetes, provided that stringent quality assurance procedures are in place and assays are standardised to criteria aligned to the international reference values. Laboratories use many different method...

A 70-year-old right-handed woman with a history of noninsulin-dependent diabetes suddenly developed involuntary movements of the right arm and leg. At that time, blood glucose levels were 500 mg/dl. The patient manifested continuous, involuntary movements on the right side of the body. Neurological examination showed severe HC-HB with superimposed dystonic posturing on the right side. The movem...

The existence of a Kodaira fibration, i.e., of a fibration of a compact complex surface S onto a complex curve B which is a differentiable but not a holomorphic bundle, forces the geographical slope ν(S) = c 1 (S)/c2(S) to lie in the interval (2, 3). But up to now all the known examples had slope ν(S) ≤ 2 + 1/3. In this paper we consider a special class of surfaces admitting two such Kodaira fi...