the set of all non-increasing non-negative integer sequences $pi=(d_1‎, ‎d_2,ldots,d_n)$ is denoted by $ns_n$‎. ‎a sequence $piin ns_{n}$ is said to be graphic if it is the degree sequence of a simple graph $g$ on $n$ vertices‎, ‎and such a graph $g$ is called a realization of $pi$‎. ‎the set of all graphic sequences in $ns_{n}$ is denoted by $gs_{n}$‎. ‎the complete product split graph on $l‎ ...

The organizer, the signaling center that specifies vertebrate axial polarity and the nervous system, is a dorsal midline mesodermal domain in the gastrula that will form prechordal plate and anterior notochord. We show that in zebrafish the organizer is not a single domain when it first arises in the nascent mesoderm at the onset of gastrulation. Rather, in the presumptive prechordal plate regi...

The concept of an "organizer" is basic to embryology. An organizer is a portion of the embryo producing signals that lead to the creation of a patterned mature structure from an embryonic primordium. Fibroblast growth factor 8 (FGF8) is a morphogen that disperses from a rostromedial source in the neocortical primordium (NP), forms a rostral-to-caudal (R/C) gradient, and regulates embryonic and ...

The articles by Carruthers and Halliday and by Hagan, Levi, and Ferrales in the present issue of Law and Social Inquiry provide a wonderful opportunity to carry out a brief reflection on the broader field of research on globalization and law. As the discussant and organizer/chair, respectively, of a panel on “Law between Globalization and National Institutions,” from which these two articles em...

background: clinical education with patient-focused learning is very important in medical education. therefore, it is very essential to select an appropriate education method. the current study was conducted to analyze the impact of simultaneous presentation of medical stager and inter in seminars provided with a pre-organizer strategy and from the students' perspective (2012-2013).  metho...

Signals released by the Spemann organizer of the amphibian gastrula can directly induce neural tissue from ectoderm and can dorsalize ventral mesoderm to form muscle. The secreted polypeptide noggin mimics these activities and is expressed at the appropriate time and place to participate in the organizer signal. Neural induction and mesoderm dorsalization are antagonized by bone morphogenetic p...

The isthmic organizer, which patterns the anterior hindbrain and midbrain, is one of the most studied secondary organizers. In recent years, new insights have been reported on the molecular nature of its morphogenetic activity. Studies in chick, mouse and zebrafish have converged to show that mutually repressive interactions between the homeoproteins encoded by Otx and Gbx genes position this o...