نتایج جستجو برای: gene cassettes

تعداد نتایج: 1142012  

Journal: :Journal of Applied Communications 1976

Journal: :Antimicrobial agents and chemotherapy 2006
Xinhui Li Lei Shi Weiqing Yang Lin Li Shinji Yamasaki

Pseudomonas aeruginosa is an opportunistic human pathogen that causes nosocomial infections. This bacterium is characterized by inherent resistance to a wide variety of antimicrobials; the inherent resistance is always mediated by antibiotic resistance genes (3, 10). A genetic element, the integron, is potentially a major agent in the dissemination of multidrug resistance among gram-negative ba...

2015
Mohammad Javad Mehdipour Moghaddam Adeleh Alsadat Mirbagheri Zivar Salehi Seyyed Mahmood Habibzade

BACKGROUND Extended spectrum beta lactamases (ESBLs) are an important cause of transferable multidrug resistance (MDR) in gram-negative bacteria. The most described ESBL genes are generally found within integron-like structures as mobile genetic elements. The aim of this study was to identify the accompanying of class 1 integrons and ESBLs in the MDR E. coli isolates. METHODS Susceptibility t...

Journal: :The Journal of antimicrobial chemotherapy 2010
Andrea T Fessler Carmen Billerbeck Kristina Kadlec Stefan Schwarz

OBJECTIVES This study focused on the correlation between geno- and phenotypic tests in the correct assessment of mecA-mediated methicillin resistance among coagulase-negative staphylococci (CoNS) and the further characterization of mecA-positive isolates. METHODS A total of 121 CoNS from cases of bovine mastitis were investigated for oxacillin susceptibility by disc diffusion and broth microd...

Journal: :Microbiology 2000
C A Clark L Purins P Kaewrakon T Focareta P A Manning

Until the discovery of the Vibrio cholerae repeat (VCR), the gene capture and expression systems termed integrons had been typically associated with antibiotic-resistance gene cassettes with usually less than five genes in an array. A method is described for the cloning of the ends of large cassette arrays. Conserved restriction sites within VCRs facilitated the mapping by Southern hybridizatio...

2015
Sheila Roitman José Flores‐Uribe Alon Philosof Ben Knowles Forest Rohwer J. Cesar Ignacio‐Espinoza Matthew B. Sullivan Francisco M. Cornejo‐Castillo Pablo Sánchez Silvia G. Acinas Chris L. Dupont Oded Béjà

Marine photosynthesis is largely driven by cyanobacteria, namely Synechococcus and Prochlorococcus. Genes encoding for photosystem (PS) I and II reaction centre proteins are found in cyanophages and are believed to increase their fitness. Two viral PSI gene arrangements are known, psaJF→C→A→B→K→E→D and psaD→C→A→B. The shared genes between these gene cassettes and their encoded proteins are dist...

2015
Anne Louise Askou Lars Aagaard Corinne Kostic Yvan Arsenijevic Anne Kruse Hollensen Toke Bek Thomas Gryesten Jensen Jacob Giehm Mikkelsen Thomas Juhl Corydon

Lentivirus-based gene delivery vectors carrying multiple gene cassettes are powerful tools in gene transfer studies and gene therapy, allowing coexpression of multiple therapeutic factors and, if desired, fluorescent reporters. Current strategies to express transgenes and microRNA (miRNA) clusters from a single vector have certain limitations that affect transgene expression levels and/or vecto...

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