OBJECTIVE Predicting extubation failure (EF) is one of the most challenging aspects of critical care medicine. The literature on EF in neurocritical care patients is very scarce. We sought to determine the ability of traditional weaning parameters to predict EF in neurocritical patients. METHODS This is a retrospective observational study performed at a tertiary level, academic, Neurological ...

Abstract Background To investigate the indications for high-flow nasal cannula oxygen (HFNC) therapy in patients with hypoxemia during ventilator weaning and to explore predictors of reintubation when treatment fails. Methods Adult from mechanical ventilation were identified Medical Information Mart Intensive Care IV (MIMIC-IV) database. The assigned group or control according whether they rece...

BACKGROUND Diaphragmatic paralysis in newborns is related to brachial plexus palsy. It can cause respiratory failure necessitating prolonged mechanical ventilation and subsequent extubation failure. CASE PRESENTATION We present a two-hour-old male newborn with a birth weight of 4500 grams who had a right-sided brachial plexus palsy and right diaphragmatic paralysis due to shoulder dystocia. H...

We read with great interest the article by Thille et al. [1] and commend the authors on their work. It is accepted that noninvasive ventilation (NIV) used prophylactically reduces post-extubation respiratory failure, but its impact on reintubation remains contentious [2]. Therefore, the current study, which reports reduced rates of reintubation from 28 % to 15 % in high-risk populations with NI...

INTRODUCTION The purpose of this study was to evaluate if ultrasound derived measures of diaphragm thickening, rather than diaphragm motion, can be used to predict extubation success or failure. METHODS Sixty-three mechanically ventilated patients were prospectively recruited. Diaphragm thickness (tdi) was measured in the zone of apposition of the diaphragm to the rib cage using a 7-10 MHz ul...

INTRODUCTION Availability of objective criteria for predicting successful extubation could avoid unnecessary prolongation of mechanical ventilation and/or inadvertent premature extubation, but the predictors of successful extubation in children are unclear. This study was performed to detect and validate respiratory function predictors of successful extubation in children admitted to the pediat...

OBJECTIVE To identify the causes of delayed extubation in patients planned for fast tract extubation during cardiac surgery. METHODS A prospective observational study was conducted at cardiothoracic unit of Aga Khan University Hospital for the period of one year. All elective coronary artery bypass graft (CABG) surgery patients, between the ages of 35-75 years with LVEF > or = 40 percent were...