Germanium recovery from coal fly ash by hydrometallurgical procedures was studied at the pilot scale (5 kg of fly ash/h). Results were used to design the equipment of a demonstration-sized plant (200 kg of fly ash/h). The process is based on hydrometallurgical operations: firstly a germanium extraction from fly ash by leaching and a consequent Ge separation from the other elements present in th...

AIMS This study sought to investigate the possible influence of different bifurcation stenting techniques on stent deformation, physical stress, and drug elution using a virtual tool that includes structural, fluid dynamics and drug-eluting numerical models. METHODS AND RESULTS A virtual bench test based on explicit dynamics modelling was used to simulate procedures on bifurcated coronary ves...

Moore and Stein (1) have reviewed the work of Boardman and Partridge and others on problems encountered in attempting the chromatography of nonbasic proteins on Amberlite IRC-50 by elution analysis with the use of buffers of constant composition for the elution. Boardman and Partridge (2) suggested that the difficulty in achieving reversible equilibrium binding was due to hydrogen bonding betwe...

An improved method for evaluating drug release behaviour of drug-eluting embolization beads (DEBs) was developed utilizing an open-loop flow-through system, in which the beads were packed into an occlusive mass within the system and extracted with a flowing elution medium over time. Glass beads were introduced into the beads mass in order to ensure laminar flow, reduce dead volume and improve r...

The use of aqueous mixed micellar system consisting of sodium dodecyl sulfate (SDS) and polyoxyethylene (23) dodecanol (Brij-35) as the mobile phase in reversed-phase liquid chromatography was studied. A group of chlorophenols was used as the test mixture. Adding organic modifier to the system showed that the use of low concentrations of organic additives improves efficiency in SDS/Brij-35 mixe...

To address concerns of late and very late stent thrombosis associated with first generation drug-eluting stent technology, novel approaches are being tested including stents with bioabsorbable polymers (including Biomatrix FlexTM, NoboriTM and SynergyTM), polymer-free drug delivery systems (including BiofreedomTM and Yukon®) and drug-eluting balloons (including Sequent PleaseTM, Dior® II and Pa...

Functional and clinical transfusion studies were carried out on granulocytes eluted from nylon filters using ACD Saline solutions and 20% CPD Plasma ACD Saline solutions. Although the average volume of blood and total number of granulocytes filtered were the same, the yield of granulocytes eluted form the filters was 20% greater when 20% CPD plasma was in the eluting solution. Function studies ...

Antibiotics are commonly mixed with polymethylmethacrylate (PMMA) cement to suppress severe periprosthetic infections associated with total joint arthroplasty. The relationship between antibiotic concentration and the resulting elution kinetics remains unclear. The purpose of this study was to characterize the release of daptomycin from PMMA cement and the subsequent effects on mechanical prope...