The development of anticancer metal-based drugs was attempted by reacting dodecyl amine with selenious acid to produce a quaternary ammonium salt which was then converted to copper and cobalt cationic complexes via complexing the first compounds with copper (II) or cobalt (II) ions. The surface properties of these surfactants were investigated. The surface properties studied included critical m...

 Many systemic factors may influence the healing process. The present study aimed to analyze histological modifications induced by the presence of Ehrlich ascites tumors on laparotomic surgical scars in BALB/c mice. A total of 52 mice were used. Half of the mice were injected with Ehrlich tumor cells, and 7 days later (day 7) all mice underwent laparotomy. On day 11, the scar was resected i...

The effect of viruses on malignant tumors has been examined by a number of investigators (9). With the conversion of solid tumors into ascites form (8), however, it has become possible to carry out a more definitive study of the growth of viruses in cancer cells. The present communication deals with the normal growth characteristics of a hyperdiploid line of the Ehrlich ascites carcinoma of the...

The concentrations of sodium, potassium, magnesium, cal cium, chloride, and phosphate were determined in Ehrlich ascites tumor cells and fluid after 5, 7, 9, and 12 days of growth. Material obtained after the 12th day showed peculiar intra cellular ion patterns, presumably related to the near-terminal condition. Material drawn after 5-9 days of growth represented viable cells. The intracellular...

If these three high-pH complications are corrected for, then the variation of kcat with pH in all three cases is governed by a single, non-essential ionization, around pH8.2 in the presence of Mg2+, and pH6 in its absence. It is tempting to equate this ionization with that obtained for conventional substrates [pH8.4 with Mg2+ and pH6.5 without (Tenu et al., 1971)], but, if the same species is r...