The effects of 4-aminopyrazolo(3,4-d)pyrimidine (APP), alone or in combination with azaserine, thioguanine, and 6-mercaptopurine, have been tested in Ehrlich ascites carcinoma, Sarcoma 180 ascites, 6C3HED ascites lymphosarcoma, Mecca ascites lymphosarcoma, and TAS ascites carcinoma. The Ehrlich ascites carcinoma is the only tumor of this series which responds to APP. Several combinations of APP...

background: present investigations were carried out to evaluate an ethanolic extract of oxalis corniculata linn. for its anticancer and antioxidant activity in ehrlich acsites carcinoma (eac) - induced in swiss albino mice. methods: cancer was induced in mice by aspiration of peritoneal fluid of eac inoculated mice and diluted to get 1x10 6 cells/ml in phosphate buffer. cancerous animals were d...

The objective of this paper was to study the anti-Ehrlich ascites carcinoma effect of purified toad venom extract and its mechanism. Mouse model of Ehrlich ascites carcinoma was established with cisplatin as the control to observe the inhibitory effect of purified toad venom extract on malignant peritoneal effusion in mice. The results showed that compared with the control group, ascites volume...

Ehrlich ascites carcinoma is a spontaneous murine mammary adenocarcinoma adapted to ascites form and carried in outbred mice by serial intraperitoneal (i/p) passages. The previous work from our laboratory showed that honey having higher phenolic content was potent in inhibiting colon cancer cell proliferation. In this work, we extended our research to screen the antitumor activity of two select...

The inhibitor of vaccinia hemagglutinin appearing in the ascites of the Ehrlich carcinoma of the mouse has been characterized and partially purified. The biological and chemical properties of this substance indicate that it has much in common with inhibitors reported previously in other biological material and suggest that, like these, it, too, is mucoprotein in nature. The inhibitor is found n...

The substrate specificity of hexokinase preparations from Ehrlich ascites cells, a spontaneous adenocarcinoma, Jensen sarcoma, and Walker carcinoma was studied with a number of sugars which differed in structure from glucose at one or more carbon atoms used as substrates. A marked variat ion in specificity was found. The preparations from Jensen sarcoma and Ehrlich ascites cells were relatively...

5 -Hydroxy-2-formylpyridine thiosemicarbazone (5-HP) is highly active intraperitoneally against leukemia L-1210, Ehrlich ascites carcinoma, and lymphoma L-5 178Y over a broad dose range. 5-HP is also active on leukemia L-l210 and the Ehrlich ascites carcinoma by delayed treatment. Activity by oral routes or subcutaneously is poor. Moderate activity is displayed against the Lewis lung carcinoma ...

Several attempts in this laboratory in the last @ or 3 years to culture the Knebs-@ ascites carcinoma of mice had failed. The maximum survival time of the cells in culture was about 10 days. The media used always contained chicken embryo ex tract (CEE). Later, during efforts to develop a culture medium and technic by which single cell cultures could readily be initiated for single-cell irradiat...

5 -Hydroxy-2-formylpyridine thiosemicarbazone (5-HP) is highly active intraperitoneally against leukemia L-1210, Ehrlich ascites carcinoma, and lymphoma L-5 178Y over a broad dose range. 5-HP is also active on leukemia L-l210 and the Ehrlich ascites carcinoma by delayed treatment. Activity by oral routes or subcutaneously is poor. Moderate activity is displayed against the Lewis lung carcinoma ...

Aqueous and alcoholic extracts of curcuma amda roxb. rhizomes have been evaluated for its anti tumour activity in Swiss albino mice. Alcoholic extract exhibited more potent anti tumour activity than aqueous extract. In-vitro cytotoxicity studies were confirmed by brine shrimp bioassay method. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were...