Adsorption–desorption of diethylamine salicylate on latex particles have been studied. Time, pH, concentration and electrokinetic characteristics of the active principle at which maximum absorption occurred were determined. Desorption of the drug from latex polymer particles was studied in three different vehicles. The findings suggest that solubility of diethylamine salicylate is the main fact...

Objective(s): Nanocarriers are drug delivery vehicles, which have attracted the attention of researchers in recent years, particularly in cancer treatment. The encapsulation of anticancer drugs using protein nanocages is considered to be an optimal approach to reducing drug side-effects and increasing the bioavailability of anticancer drugs. Epirubicin (EPR) is an active chemotherapeutic medica...

Researches on drug delivery system (DDS) have made incredible progress, but there are still problems such as insufficient targeting and undesirable treatment efficiency. To improve the above problems, a stem cell-based DDS was developed. Stem cell its derivatives (cell membranes, extracellular vesicles/exosomes) been used important vehicles in of number human key diseases, genetic cancer so on....

Drug delivery across the blood–brain barrier (BBB) has several challenges, especially toward targeting neurological diseases, due to tight and selective function of BBB. Several structural functional components this contribute restricting drug entry, such as interendothelial junctions (TJs), efflux transporters, drug-metabolizing enzymes, crosstalk between cells neurovascular unit. Among differ...

A targeted drug delivery system is the need of the hour. Guiding magnetic iron oxide nanoparticles with the help of an external magnetic field to its target is the principle behind the development of superparamagnetic iron oxide nanoparticles (SPIONs) as novel drug delivery vehicles. SPIONs are small synthetic γ-Fe₂O₃ (maghemite) or Fe₃O₄ (magnetite) particles with a core ranging between 10 nm ...

Electric vehicle charging station have become an urgent need in many communities around the world, due to increase of using electric vehicles over conventional vehicles. In addition, establishment stations, and grid impact household photovoltaic power generation would reduce feed-in tariff. These two factors are considered propose setting up stations at convenience stores, which enable energy b...

It is, sometimes, desirable to maintain a constant plasma drug concentration within the therapeutically effective concentration range. The use of high viscosity hydromiscible vehicles such as hydrophilic gels, is one of various approaches for controlled drug delivery, and represents an important area of pharmaceutical research and development. Of these systems, Pluronic F-127 (PF-127) provides ...

Objective(s): In this work, electrospun nanofibers were explored as drug delivery vehicles using tetracycline as a model drug.  Nanocomposite fibers including chitosan (CS)/poly (ethylene oxide) (PEO) and antibiotic were successfully prepared using electrospinning. CS blended with PEO considering a weight ratio of (90/10), and then, nanofibrous samples were successfully e...