نتایج جستجو برای: codon optimization

تعداد نتایج: 338257  

Journal: :Genetics and molecular research : GMR 2015
W Du J Xia Y Zhang M J Liu H B Li X M Yan J S Zhang N Li Z Y Zhou W Z Xie

Myostatin propeptide can inhibit the biological activity of myostatin protein and promote muscle growth. To express myostatin propeptide in vitro with a higher biological activity, we performed codon optimization on the sheep myostatin propeptide gene sequence, and mutated aspartic acid-76 to alanine based on the codon usage bias of Pichia pastoris and the enhanced biological activity of myosta...

Journal: :archives of clinical infectious diseases 0
maryam vaezjalali department of microbiology, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran hanieh rezaee department of microbiology, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran; urology and nephrology research center, shahid beheshti university of medical sciences, tehran, ir iran hosein goudarzi department of microbiology, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran; department of microbiology, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran. tel.:+98-2123872556, fax: +98-2122439964

conclusions: premature stop codon in the s gene was observed in all countries with evaluable hbv genome sequences. co-existence of detectable hepatitis b surface antigen (hbsag) and s gene premature stop codon was inconsistent with other studies. investigations on yield truncated hbsag are suggested to determine if they can affect elisa hbsag results. background: we have previously reported on ...

2018
Changqing Liu Xiao Men Hailin Chen Meijie Li Zhaorui Ding Guoqiang Chen Fan Wang Haobao Liu Qian Wang Youshuang Zhu Haibo Zhang Mo Xian

Background Styrene is a versatile commodity petrochemical used as a monomer building-block for the synthesis of many useful polymers. Although achievements have been made on styrene biosynthesis in microorganisms, several bottleneck problems limit factors for further improvement in styrene production. Results A two-step styrene biosynthesis pathway was developed and introduced into Escherichi...

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