ANRIL (Antisense Noncoding RNA in the INK4 Locus), a long non-coding encoded human chromosome 9p21 region, is critical factor for regulating gene expression by interacting with multiple proteins and miRNAs. It has been found to play important roles various cellular processes, including cell cycle control proliferation. Dysregulation of associated several diseases like cancers cardiovascular dis...

A variety of RNA molecules have been found in the last two decades with a wide range of biological functions beyond the traditional roles of the well-known coding RNA (messenger RNA or mRNA) and non-coding RNA (ribosomal and transfer RNA). Over twenty years ago, the discovery of the catalytic properties of the RNA subunit of the ribonuclease P and the self-splicing activity of group I introns s...

Submit Manuscript | http://medcraveonline.com Abbreviations: PBMC: Peripheral Blood Mononuclear Cells; TME: Tumor Microenvironment; FFPE: Formalin-Fixed ParaffinEmbedded; OCT: Optimal Cutting Media; RNA: Ribonucleic Acid; DNA: Deoxy Ribonucleic Acid; TCR: T Cell Receptor; TIL: Tumor Infiltrating Lymphocytes; IHC: Immunohistochemistry; Cytof: For Cytometry by Time of Flight; Elispo: Enzyme Linke...