We present a framework for cardiac motion recovery using the adjustment of an electromechanical model of the heart to cine Magnetic Resonance Images (MRI). This approach is based on a constrained minimisation of an energy coupling the model and the data. Our method can be seen as a data assimilation of a dynamic system that allows us to weight appropriately the confidence in the model and the c...

Introduction Cine DENSE (Displacement Encoding with Stimulated Echoes) is a quantitative MRI method for imaging myocardial displacement and strain. Typically, cine DENSE images of the heart are acquired in a short-axis plane, and the in-plane circumferential and radial displacements and strains are measured. However, quantitative imaging of longitudinal myocardial motion is also important, as i...

ECG-gated cardiac MRI in the mouse is hindered by many technical difficulties in ECG signal recording inside static and variable high magnetic scanner fields. The present study proposes an alternative robust method of acquiring auto-gated cine images in mouse heart. In our approach, a motion synchronization signal is extracted from the echo peak MR signal of a nontriggered radial acquisition. T...

Background Small-Animal Look-Locker Inversion Recovery (SALLI) is a novel imaging method that generates simultaneously cardiac T1 maps, cine MR and inversion recovery-prepared images for high heart rates. T1 mapping by SALLI has been tested and compared with histology, however the assessment of left ventricular (LV) function has not yet been validated. Our aim was to compare the measurement of ...

Background Although cine magnetic resonance imaging (MRI) is considered the gold standard for evaluation of left ventricular (LV) volumes, mass, and systolic function, assessment of diastolic filling is still challenging. The aim of this study was to assess the impact of LV mass on diastolic function by time-volume curve obtained from cine MRI in patients with dilated cardiomyopathy (DCM) or hy...

Thermoluminescent dosimetry was used to measure the radiation exposure to the skin, thyroid and gonads in 50 consecutive pediatric patients undergoing cardiac catheterization and angiocardiography using cine photofluorography. Average exposures were 17.1 R to the skin, 2.3 R to the thyroid and 0.1 R to the gonads. Fluoroscopy accounted for approximately 80% of the skin and thyroid exposure and ...

Cine-DEMR is a new cardiac imaging technique which combines aspects of Cine and Delayed Enhancement MR. Like Cine, it displays the heart beating over time allowing for the detection of motion abnormalities. Like DEMR, non-viable (dead) tissues appear with increased signal intensity (it has been shown that the extent of non-viable tissue in the left ventricle (LV) of the heart is a direct indica...

Background CINE imaging of the mouse heart is an established technique on high-field small animal MRI systems. The current imaging protocols normally comprise twodimensional CINE imaging in 2and 4-chamber geometry and a stack of short axis views for full functional coverage of the heart. For SNR constraints, acquisition times are still in the minute range for a single 2D slice, yielding rather ...

Methods Thirteen patients referred to the CMR lab for evaluation of undiagnosed cardiomyopathy were prospectively enrolled. All patients were in regular cardiac rhythm and able to breath-hold. Standard segmented k-space images (including cine, velocity mapping (VM), and late-gadolinium enhancement (LGE)) were acquired during breathhold; real-time images (including cine, VM, and LGE) were acquir...

Cardiovascular magnetic resonance (MR) imaging can provide three-dimensional analysis of global and regional cardiac function with great accuracy and reproducibility. Quantitative assessment of regional function with cardiac MR imaging previously was limited by long acquisition times and time-consuming analysis. The use of steady-state free precession cine MR imaging substantially improves asse...