Cyclophosphamide is one of the chemotherapeutics for cancer, however this drug has severe side effects in multiple organs and a well-known mutagenic agent. In work protective activity antioxidant-rich Carob (Ceratonia siliqua L.) pods leaves extracts against cyclophosphamide induced genotoxicity was studied. Safety these evaluated acute subacute toxicity tests at dose 1500 mg/kg/day albino rats...

Abstract This study focused on the colloidal stability enhancement of iron oxide nanoparticles synthesized using aqueous extract Ceratonia siliqua L. (carob pod) by optimizing synthesis parameters. The parameters were determined as concentration ions, extract, pH temperature, stirring rate, and reaction time. significance studied factors in controlling particle size distribution was quantitativ...

Objective: Carob (Ceratonia siliqua L.) is an evergreen tree with fruits that have potent antioxidant activity. The aim of this study was to investigate alleviative effects of carob fruit hydro-alcoholic extract (CFHAE) against reproductive toxicity induced by lead (Pb) in male mice. Material and Methods: Forty-two NMRI adult male mice were randomly categorized into 7 groups (N=6). Group ...

The purpose of this study was to determine the in vivo glycemic index of carob tablets with healthy subjects and to determine the in vitro glycemic index of carob tablets and carob flour by the hydrolysis index. Seven healthy volunteers consumed portions of carob tablets containing 26g of available carbohydrate. Their capillary blood was taken at intervals after carob or glucose consumption. Th...

Concentrated whole extracts of the immature fruit of carob and 3 fractions derived from this extract have been shown to inhibit the gibberellic acid induced growth of pea seedlings. The inhibition can be completely reversed by increasing the amount of gibberellic acid. The inhibitors do not reduce the endogenous growth of seedlings but only that induced by gibberellic acid. One of the fractions...