The endogenous cardiac steroid-like compounds, endogenous ouabain (EO) in particular, are present in the human circulation and are considered putative ligands of the inhibitory binding site of the plasma membrane Na(+)-K(+)-ATPase. A vast amount of data shows that, when added to cell cultures, these steroids promote the growth of cardiac, vascular, and epithelial cells. However, the involvement...

introduction: iiron oxide nanoparticles (io np) have an increasing number of biomedical applications. to date, the potential cytotoxicity of these particles remains an issue of debate. little is known about the cellular interaction or toxic effects of io np on differentiation of stem cells. the aim of the present study was to investigate the possible toxic role of different doses of io np in di...

the aim of our work was to compare cytotoxic and membrane-damaging effects of o. majorana l. essential oil and linalool on hep g2 and to investigate their possible protective (antioxidant) effects against h2o2 induced membrane damage. the oils were investigated by gc and gc-ms and antioxidant activity was evaluated by dpph and -carotene–linoleic acid assays. assessment of cell viability was ma...

statement of the problem: the maintenance of viable periodontal ligament cells is the most important issue in the long-term preservation of avulsed teeth. purpose: the aim of this study was to assess aloe vera as a new storage media in maintaining the cell viability of dry-stored teeth in comparison with soy milk, hank`s balanced salt solution (hbss), and milk. materials and method: twenty one ...

Background: Recently, iron oxide nanoparticles have attracted attention in various diagnosis and treatment fields. The aim of the present study was to investigate the cytotoxicity of various concentrations and incubation times of dextran-coated iron oxide nanoparticles (DIONPs) on HeLa and MCF-7 cancerous cell lines. Methods: This in-vitro study was conducted at Pharmaceutical Sciences Researc...

introduction: following avulsion, the periodontal ligament (pdl) cells are at risk of necrosis. to achieve a favorable survival prognosis, the pdl cells must be kept viability. therefore, immediate replantation is considered as the treatment of choice and in case it is not possible, storing the tooth in an appropriate storage media should be considered. oral rehydration solution (ors) is a gluc...

Introduction: Efforts are made to identify the new potential components such as anticancer drugs. Medicinal plants belonging to Euphorbia genus are widely studied with promising effects. The current study aimed at investigating the effect of ethanolic extract of the root of E. tehranica, grown in Iran, on Caco-2 human colorectal cancer cell-line. Methods: The Caco-2 cells were treated with dif...

Objective(s): Impairment of nerve cells of brain induced by hypoxia results in energy-deprivation and dysfunction, which accompanies with neurons apoptosis. Improving function of nerve cells is important for treating cerebral anoxia. This study aimed to investigate the role of Quercetin (Quer) in hypoxia-induced injury of pheochromocytoma (PC-12) cells. Materials and Methods: PC-12 cells were c...

cytotoxic effects of obturation materials were tested in presence and absence of endotoxin on human monocytes in vitro.human monocytes from thp-1 cell line were cultured. three millimeters from the tip of each resilon and gutta percha points were cut and directly placed at the bottom of the culture wells. cultured cells were exposed to gutta percha (groups g1 and g2) and resilon (r1 and r2). te...