Acyclovir (ACV), a model drug for this study, is one of the most effective drugs against viruses of the herpes group. Absorption of orally administered ACV is variable and incomplete, with a bioavailability of ca. 15-30%. The drug is absorbed in the duodenum after oral administration and hence, preparation of a floating drug delivery system (FDDS) for ACV may increase oral absorption of the dru...

BACKGROUND Periodontitis is a disease of tooth supporting tissues, and Gram-negative Bacteria are the main cause of this. Propolis has antibacterial, anti-inflammatory, and antioxidant effects due to its high polyphenol and flavonoids content. The aim of this study is the formulation of a mucoadhesive gel containing concentrated extract of propolis for treatment of periodontitis. MATERIALS AN...

OBJECTIVE To estimate the prevalence of medically unexplained symptoms in patients who most frequently attend outpatient services. DESIGN Retrospective cohort study over three years with review of case notes. SETTING Secondary care services in the South Thames (West) NHS region. PARTICIPANTS Outpatient attenders with new appointments in 1993. MAIN OUTCOME MEASURES Number of outpatient a...

Sample Size n = 30 n = 100 n = 250 Data Set / Method ACI Yang Jiang ACI Yang Jiang ACI Yang Jiang ThreePt .976 .893* .914* .961 .552* .945 .961 .387* .930* Magic .955 .999* .983* .977* .991* .969* .972* .997* .974* Mam. .957 .989* .966 .962 .996* .964 .960 .995* .968 Ion. .947 .995* .985* .948 .996* .970* .970 .990* .970* Donut .968 .966 .908* .969 .851* .971* .973* .898* .966 Bal. .979* .996* ...

vacious plant distributed across all of Korea and also cultivated in China. The root of Cynanchum paniculatum is used as a Chinese traditional medicine. Recently, the plants of genus Cynanchum of Asclepiadaceae, e.g. Cynanchum atratum, Cynanchum auriculatum and Cynanchum paniculatum, were studied for their anticancer and analgesic effects. In addition, Cynanchum paniculatum has been traditional...

In 1895 G. Schlumberger published the seal of Arkadios, protospatharios and strategos Bosporos. 2008, I. Jordanov second find similar found in Preslav. The Bosporos appeared Taktikon 975, by N. Oikonomides. According to written sources, Preslav was conquered Byzantium 971 remained under its control as long 986. Byzantine historian Leo Deacon, during negotiations with Prince Sviatoslav 971, Empe...