Between 1999 and June 2001, 55 unselected thyrotoxic patients were prescribed 200 MBq radioactive iodine (131I). None of these patients received a thionamide such as carbimazole or propylthiouracil within two weeks of treatment or subsequently. Symptom relief was achieved using beta blockers alone. Remission at one year was achieved in 84% of these patients and of these 62% were hypothyroid and...

BACKGROUND & OBJECTIVES Hyperthyroidism is associated with increased food intake, energy expenditure and altered body composition. This study was aimed to evaluate the role of adipocytokines in weight homeostasis in patients with hyperthyroidism. METHODS Patients (n=27, 11men) with hyperthyroidism (20 Graves' disease, 7 toxic multinodular goiter) with mean age of 31.3±4.2 yr and 28 healthy ag...

In routine use for more than 50 years, radioiodine ((131)I) is generally considered safe and devoid of major side effects. Therefore, it is surprising that relatively many aspects of radioiodine therapy are controversial, as illustrated by recent international questionnaire studies. Our review aims at highlighting three of these areas - namely, the influence of (131)I on the course of Graves' o...

materials and methods patients were given fixed daily dose of 20 mg carbimazole for 3 months and blood samples were collected at baseline and end of the study. thirty-eight patients were recruited from the endocrine clinic, hospital universiti kebangsaan malaysia, consisting of 26 females and 12 males, age ranging from 16 to 65 years. blood samples collected before and at end of study were anal...

Euthyroid state is considered a requisite before planning thyroid surgery. Before such surgery, pharmacotherapy can be used for managing hyperthyroid state. It warrants long-term treatment with agents like imidazole class (carbimazole, methimazole) or propylthiouracil. In cases large goiters, pressure symptoms dyspnoea, dysphagia, dysphonia; surgeon would prefer quicker action than the establis...