toxicity of which on biological wastewater processes, humans, and the environment has been proven in various studies. in this study, the half maximal effective concentration (ec 50 ) of growth inhibition of cadmium, lead, and mercury was assessed on dominant bacterial species present in sequencing batch reactors (sbr). methods: biomass sample was obtained from the biological unit of the sbr est...

background lumbar plexus block (lpb) is one of the anesthetic options in the elderly patients undergoing hip surgeries. lpb could be safe because it targets somatic nerve in psoas region. effectiveness of lpb is attributed to the sufficient analgesia provided intraoperatively as well as postoperatively. adequate muscle relaxation and immobility during surgery refers to its acceptability. object...

Motivation Linkage disequilibrium (LD) block construction is required for research in population genetics and genetic epidemiology, including specification of sets of single nucleotide polymorphisms (SNPs) for analysis of multi-SNP based association and identification of haplotype blocks in high density sequencing data. Existing methods based on a narrow sense definition do not allow intermedia...

The melanocortin-4 receptor (MC4R) has important roles in regulating food intake, energy balance, and body weight in mammals. In pigs and cattle, MC4R mutations have been identified as genetic markers for growth and traits. Compared with abundant research conducted on other livestock species, little is known about mutations of the ovine MC4R gene. We investigated the affect of MC4R polymorphism...

A critical aspect of long-term open-pit mine planning consists in computing a production schedule based upon a block sequencing strategy. Such a schedule should specify when and if blocks should be extracted in such a way as to maximize NPV, while satisfying wall-slope and production capacity constraints. It is well known that this problem can be modeled with integer programming (IP). However, ...

UNLABELLED Automated genome sequencing procedure is enriching the sequence database very fast. To achieve a balance between the entry of sequences in the database and their analyses, efficient software is required. In this end PHYSICO2, compare to earlier PHYSICO and other public domain tools, is most efficient in that it i] extracts physicochemical, window-dependent and homologousposition-base...

Rapid advances in next-generation sequencing technologies are revolutionizing genomics, with data sets at the scale of thousands of human genomes fast becoming the norm. These technological leaps promise to enable corresponding advances in biology and medicine, but the deluge of raw data poses substantial mathematical, computational and statistical challenges that must first be overcome. This t...

A new design method of output feedback type tracking sliding mode control (SMC) is proposed in this paper. Stability of the control system and the tracking performance to the reference input are achieved by using the parallel feedforward compensator (PFC), which guarantees almost strict positive realness (ASPR) of the plant, and the so-called internal model. Effectiveness of the method is shown...

Block copolymer nano-micelles are especially important in cancer treatment because of their fine dimensions. In this article, three systems of amphiphilic copolymers with similar lengths and different ratios of the hydrophobic and hydrophilic chains are studied using implicit-solvent coarse-grained molecular dynamics simulations. The factor fphil is defined as the ratio of the number...

objective mustard gas (mg) is a poisoning chemical, mutagenic and carcinogenic alkylating agent. it is used during world war i and also iran-iraq conflict. the p53 tumor suppressor gene is involved in the pathogenesis of malignant disease. the aim of this study is to determine possible mutation in p53 gene of lung sample from mustard gas exposed patients. material and methods twelve lung biopsy...