Background: Wound infection is a highly common problem in hospital settings, where microbes are often resistant and difficult to treat due rapid exposure antibiotics. While treating wound infection, bacteria enter the deep tissue; as therapy needs long time, have sufficient time develop biofilm, which makes them much more Objectives: The current study was performed identify wound-infecting dete...

Bacteria control gene expression by quorum sensing (QS) mechanism owing to producing small signal molecules associated with population density. Both gram-positive and gram-negative bacteria use QS manage various physiological characteristics, including bioluminescence, virulence expression, biofilm formation, antibiotic resistance. Impatience balsamina is a flowering, perennial annual herb indi...

The formation of biofilm by pathogenic microorganisms has become a problem in the livestock industry since it is considered potential source infection for farm animals while increasing microbial resistance to physical and chemical agents. Some plant extracts, such as soluble wheat extract, have been shown be effective inhibiting or destroying certain micro-organisms under specific conditions. o...

Marine bacteria contribute significantly towards the fouling consortium, both directly (modern foul release coatings fail to prevent "slime" attachment) and indirectly (biofilms often excrete chemical cues that attract macrofouling settlement). This study assessed the natural product anti-biofilm performance of an extract of the seaweed, Chondrus crispus, and two isolated compounds from terrest...

Porphyromonas gingivalis is a major pathogen of chronic periodontitis and exists in a biofilm on the surface of the tooth root. Oxantel, a cholinergic anthelmintic and fumarate reductase inhibitor, significantly inhibited biofilm formation by P. gingivalis and disrupted established biofilms at concentrations below its MIC against planktonic cells. Oxantel was more effective against P. gingivali...

Bacterial biofilms are communities of microorganisms residing within a polysaccharide matrix. Dental plaque, slimy coating in tanks, and algal mats on bodies of water are examples of biofilms. It is well accepted that biofilms play important role in bacterial persistence and antibiotic resistance in chronic infections. It is acknowledged that the majority of microbial cells on earth are living ...

Multispecies biofilms are becoming increasingly recognized as the naturally occurring state in which bacteria reside. One of the primary health issues that is now recognized to be exacerbated by biofilms are chronic, nonhealing wounds such as venous leg ulcers, diabetic foot ulcers, and pressure ulcers. Arguably three of the most important species associated with multispecies biofilms that our ...

This review highlights the current situation of antimicrobial resistance and the use of magnetic nanoparticles (MNPs) in developing novel routes for fighting infectious diseases. The most important two directions developed recently are: (i) improved delivery of antimicrobial compounds based on a drastic decrease of the minimal inhibition concentration (MIC) of the drug used independently; and (...

AIMS In this study, we examined the biofilm formation of 75 Salmonella enterica serovar Typhimurium (Salm. Typhimurium) human clinical isolates and the effect of subinhibitory concentrations (sub-MICs) of gentamicin, ciprofloxacin and cefotaxime on biofilm formation and exopolysaccharides (EPS) production. METHODS AND RESULTS Quantification of biofilm formation and EPS production were carried...

Desulfovibrio vulgaris Hildenborough is a Gram-negative sulfate-reducing bacterium (SRB). It has ability to adhere to the surfaces forming biofilm. It can seriously impact environmental sites including metal pipelines, oil repositories and radionuclide waste sites. Due to increased antibiotic resistance among bacterial pathogens, treatment for infectious diseases is getting ineffective. There s...