growth of the prostate gland, also development of benign prostatic hyperplasia (BPH) is an androgen-dependent functions. Testosterone plays a major role in the prostate gland. Rat prostate gland is one of the most widely used models of animals in investigation. The rat prostate gland consisted of five lobes; the ventral, anterior, dorsal, lateral type 1 and latteral type 2. The goal of present ...

The histopathological diagnosis of prostatic adenocarcinoma is challenged by the existence numerous benign mimics. Most these lesions have no clinical significance and many do not need to be reported. Their relevance lies in risk that they are misinterpreted as cancer. This review presents features mimics discusses their distinction from most often misdiagnosed cancer atrophy its variants, incl...

BACKGROUND Although several studies have confirmed the association of xenotropic murine leukemia virus-related virus (XMRV) and prostate cancer, this association is still controversial, as most studies did not detect XMRV in prostate tissue samples. Furthermore, some genetic and epidemiological studies have highlighted a role for RNase L polymorphisms, particularly R462Q, in the progression of ...

OBJECTIVE To evaluate the efficacy and safety of photoselective prostate vapourisation with 120 w potassium titanyl phosphate laser in benign prostate hyperplasia patients receiving oral anti-coagulant therapy. METHODS The retrospective study was conducted at Istanbul Hisar International Hosptial and comprised 63 male patients who were on anti-coagulant therapy for comorbidities and who under...

The TUNA device is a unique system that uses radiofrequency energy to ablate the obstructing prostate adenoma. Although the clinical data are preliminary, they appear to provide improvement in symptom scores and peak flow rates, although somewhat less than TURP. A prospective, randomized trial comparing TUNA to TURP is under way, which should answer many of the questions regarding the safety an...

BACKGROUND A single nucleotide variation within catechol-o-methyl transferase (COMT) gene may alter the COMT enzyme activity level. Polymorphism of Val158Met in the COMT gene has been related to malignancy. In this regard, a study was carried out to find a possible association between the COMT gene polymorphism in patients with sporadic prostate cancer (PCa) and benign prostatic hyperplasia (BP...

Transurethral resection of the prostate is the most common surgery for benign prostatic hyperplasia. However, it doesn't work best for men with very large prostate and bladder stones. Herein we report our initial experience with concomitant laparoendoscopic single-site surgery and finger-assisted single-port transvesical enucleation of the prostate for the treatment of the condition.