نتایج جستجو برای: apobec3g

تعداد نتایج: 713  

Journal: :Journal of Public Health in Africa 2018

2014
Luda S. Shlyakhtenko Alexander J. Lushnikov Ming Li Reuben S. Harris Yuri L. Lyubchenko

The APOBEC3 family of DNA cytosine deaminases functions to block the spread of endogenous retroelements and retroviruses including HIV-1. Potency varies among family members depending on the type of parasitic substrate. APOBEC3A (A3A) is unique among the human enzymes in that it is expressed predominantly in myeloid lineage cell types, it is strongly induced by innate immune agonists such as ty...

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