SINCE thiouracil was introduced to clinical therapeutics in I943, antithyroid treatment for thyrotoxicosis has widely increased and proved more and more effective as the years have passed, partly as the result of experience but also through the use of more effective agents, such as carbimazole and methimazole. It is thus possible now to assess their relative value in comparison with surgical tr...

O BJECTIVE: The goal of this study was to modify and optimize the screening and diagnostic procedures of unexplained recurrent abortion. Antithyroid antibodies, parvovirus B19 (B19V) and cytomegalovirus (CMV) infections, which were usually overlooked in clinical practice of handling cases of recurrent abortion, were studied to evaluate their role in the pathogenesis of recurrent first trimester...

Antithyroid drugs are widely used to treat hyperthyroidism, especially Graves' disease, but they tend to cause agranulocytosis, which increases the mortality rate. Granulocyte colony-stimulating factor decreases the duration of recovery from agranulocytosis. We retrospectively studied cases of antithyroid drug-induced agranulocytosis over the past 10 years in a northern Taiwan medical center. A...

Twenty-one samples of water were collected from commercial egg production farms in Georgia with or without a history of fatty liver syndrome. These samples plus a sample of water from the University of Georgia Poultry Farm were analyzed for various mineral elements by atomic absorption, direct reading emission spectroscopy and by neutron activation. Water samples from farms with a history of fa...

Accepted 21 August 1996 A 78-year-old woman presented with fever and a sore throat for five days. Oral Augmentin (amoxicillin/clavulanate potassium) did not reduce the fever. Seven weeks prior to this episode Graves' disease had been diagnosed and treatmnent with methimazole 40 mg once a day and propanolol 10 mg qid was started. On admission, her temperature was 37.6°C, blood pressure was 100/7...

Hashimoto's encephalopathy is defined by the coexistence of encephalopathy and antithyroid antibodies. We report two cases of adult-onset temporal lobe epilepsy with subacute cognitive decline, high titers of antithyroid antibodies, multi-antiepileptic drug hypersensitivity, and good response to immunomodulatory treatment. The relevance of multidrug hypersensitivity in the setting of adult-onse...

patients with amultinodular thyroid gland, autonomous nodules, or latent Graves-Basedow disease due to increased thyroid hormone production and release. Its incidence is 1.7%. Areas with adequate iodine intake have a low incidence of hyperthyroidism induced by excess iodine intake. Euthyroid patients with some prior episode of postpartum thyroiditis, type 2 amiodarone-induced thyrotoxicosis, or...