Inonotus obliquus (IO) is parasitic mushroom that grows on birch and other trees in Russia, Korea, Europe and United States. However, IO is not readily available for consumption due to its high cost and difficult growth. In this regard, IO was inoculated on germinated brown rice (GBR) in the present study and the antioxidant and anti-inflammatory activities of the IO grown on germinated brown r...

BACKGROUND Chalcone, an important intermediate of flavonoid synthetic pathway, has been shown to exhibit diverse biological and pharmacological activities such as anti- cancer, antioxidant, anti-inflammatory, etc. RESULTS In this study, a novel series of chalcones fatty acid esters 5b-e and 6b-e have been synthesized via the reaction of the respective chalcones with either palmitic or stearic...

Unbalanced oxidant and antioxidant status played an important role in myocardial infarction. The present study was a clinical trial combined preclinically with targeted agent against cardiovascular injuries and ischemia in vivo model. We tried to confirm the association of unbalanced oxidant and antioxidant status with coronary chronic total occlusion (CTO) in 399 very old patients (80~89 years...

background and objectives: dorema ammoniacum d. don (apiaceae) is a monocarpic plant endemic to central iran. the gum resin of this species is a known therapeutic agent in iranian, indian and western traditional medicines. the aim of the present study was to investigate essential oil constituents and evaluation of antioxidant and antibacterial activities of the essential oils and extracts of d....

AbstractFerulago angulata Boiss. known in Iran as Chavir, has some bioactive compounds having antioxidant activity. Because of its antioxidant activities, it sounded Chavir extract can be a good candidate for finding chemopreventive agents having inductive apoptosis properties on cancer cells. In this study, the cytotoxic effects and proapoptotic activities of Chavir’s leaf and flower extracts ...

Background & Aim: Melissa officinalis L. (lemon balm) a valuable medicinal plant in herbal medicine is native to the eastern Mediterranean region and western Asia. It is a traditional herbal medicine, which enjoys contemporary usage as a mild sedative, spasmolytic and antibacterial agent. The objective of this study was to assess the effects of climate on quality and q...

peganum harmala l. (zygophyllaceae) is one of the most important medicinal plants had been used in traditional medicine in north of iran as anti parasite, anti inflammatiom, anti tumor and anti infection. the aim of this study was to evaluate of ecological factors , ethno pharmacology and record of the relationship between secondary metabolites content and their antioxidant activity in seeds ex...

in this study, we examined the antioxidant activities of methanolic extract of three endemic species of salvia from iran (s. lachnocalyx, s. reuterana and s. sahendica) employing various established in vitro systems including ferric reducing antioxidant power, trolox equivalent antioxidant capacity assay and scavenging of 1,1-diphenyl-2-picrylhydrazyl radical. the results revealed that s. reute...

We demonstrate that the garlic-derived chemopreventive agent allicin and the related anamu-derived petivericin are poor radical-trapping antioxidants in lipid bilayers, but that the in situ reaction of a lipophilic analog and a hydrophilic thiol yields an extremely potent radical-trapping antioxidant that can be recycled in the presence of excess thiol.

Silymarin is the active ingredient of milk thistle. Several studies proved that silymarin has antioxidant, anti-inflammatory and anti-cancer properties. Silymarin is widely used for treatment of hepatic and biliary disorders, renal toxicity and is recently used as adjuvant agent for treatment of cancer.