To prevent microbial growth, chemical solvents are typically utilized. However, hazardous to human health with low antimicrobial effects. Metallic-element (such as copper, silver, and gold) nanoparticles have many applications in biotechnology biomedicine. Copper (CuNPs) efficient owing their antimicrobial, anti-inflammatory, anti-proliferative properties. The objective of this study was perfor...

Abstract Objectives We and others have shown that Aspilia pluriseta is associated with various biological activities. However, there a lack of information on its cytotoxicity. This has created an gap about the safety A. extracts. As extension to our recent publication antimicrobial activity phytochemical characterization root extracts, here we report cytotoxicity tested solvent fractions. evalu...

Zinc is a redox-inert trace element that second only to iron in abundance biological systems. In cells, zinc typically buffered and bound metalloproteins, but it may also exist labile or chelatable (free ion) form. plays critical role prokaryotes eukaryotes, ranging from structural catalytic replication demise. This review discusses the influential properties of on various mechanisms bacterial ...

Abstract Bacterial meningitis is a serious infection of the central nervous system that affects people all over world. Streptococcus pneumoniae and Neisseria meningitidis are most common pathogens causing meningeal inflammation in Europe. Treatment with standard antibiotics becoming ineffective, not only due to their inability cross blood-brain barrier, but also rising antibiotic resistance. As...

The expansion of tools against HIV transmission has brought increased interest in epidemiological models that can predict the impact of these interventions. The EMOD-HIV model was recently compared to eleven other independently developed mathematical models of HIV transmission to determine the extent to which they agree about the potential impact of expanded use of antiretroviral therapy in Sou...

conclusions our work suggested that pomegranate (punica granatum l.) peel has potential antifungal activity against candidiasis, and it is an attractive option for the development of new management strategies for candidiasis. results maximum inhibitions were attributed to peel extract of the pomegranate cultivar against candida species. the greatest antifungal inhibition among the eight differe...

OBJECTIVES Nebulized hypertonic saline (HTS) has beneficial effects including reducing pulmonary exacerbations in Cystic Fibrosis (CF) patients. Several mechanisms may explain these effects but antimicrobial activity of NaCl remains largely unexplored. We aimed to measure the antimicrobial effect of NaCl on Pseudomonas aeruginosa isolated from the respiratory tract in CF patients. METHODS NaC...

Current antimicrobial susceptibility testing has limited screening capability for identifying empirical antibiotic combinations to treat severe bacterial infections with multidrug-resistant (MDR) organisms. We developed a new antimicrobial susceptibility assay using automated ultra-high-throughput screen technology in combination with a simple bacterial growth assay. A rapid screening of 5170 a...

Lantibiotics are believed to have a conceivable potential be used as therapeutics, especially against clinically resistant bacterial strains. However, their low solubility and poor stability under physiological conditions limit availability for clinical studies further pharmaceutical commercialization. Nisin is readily available cheap lanthipeptide thus serves good model in the search tools eng...

Nanotechnology is considered the most exponential technology in veterinary sciences, especially animal breeding. It has also worked wonders providing good habitual conditions and a properly livable environment for animals supported by hygiene proper maintenance of feed. The achievements nanotechnology every field are surprisingly amazing but its lead livestock pre-eminent. facilitating science ...