Harmonization of clinical laboratory results means that results are comparable irrespective of the measurement procedure used and where or when a measurement was made. Harmonization of test results includes consideration of pre-analytical, analytical, and post-analytical aspects. Progress has been made in each of these aspects, but there is currently poor coordination of the effort among differ...

Selected circulating microRNAs (miRNAs) have been suggested for non-invasive screening of non-small cell lung cancer (NSCLC), however the numerous proposed miRNA signatures are inconsistent. Aiming to identify miRNAs suitable specifically for stage I-II NSCLC screening in serum/plasma samples, we searched the databases "Pubmed", "Medline", "Scopus", "Embase" and "WOS" and systematically reviewe...

BACKGROUND Researchers often group various HPV types into composite measures based on vaccine subtypes, oncogenic potential, or phylogenetic position. Composite prevalence estimates based on PCR genotyping assay results have been calculated to assess HPV infection burden and to monitor HPV vaccine effectiveness. While prevention and intervention strategies can be made based on these prevalence ...

Abstract Leishmaniasis is a zoonotic disease caused by over 20 species of protozoan parasites the genus Leishmania. Infection commonly spread sandflies and produces wide spectrum clinical signs symptoms. Therefore, from an epidemiological therapeutic standpoint, it important to detect differentiate Leishmania spp. The objective this study was combinate in silico vitro strategies evaluate analyt...

Glycan-binding proteins are commonly used as analytical reagents to detect the levels of specific glycan structures in biological samples. A detailed knowledge of the specificities of glycan-binding proteins is required for properly interpreting their binding data. A powerful technology for characterizing glycan-binding specificity is the glycan array. However, the interpretation of glycan-arra...

The growing interest in Green Analytical Chemistry (GAC) principles through the replacement of polluting analytical procedures with greener ones, has encouraged us to develop an eco-friendly stability-indicating HPLC diode array detection method (HPLC-DAD) for simultaneous determination allopurinol (ALP) and benzbromarone (BNZ). Effective separation was accomplished using Durashell C18 column (...

Introduction The heterogeneous expression of methicillin resistance in Staphylococcus aureus (MRSA) affects the efficiency of tests available to detect it. The objective of this study was to assess four phenotypic tests used to detect MRSA. Methods This is an analytical comparative study conducted among sudanese patients during period from May 2012 to July 2014, Staphylococcus aureus strains ...

introduction amblyopia is a leading cause of visual impairment in both childhood and adult populations. our aim in this study was to assess the epidemiological characteristics of the amblyopia screening program in iran. materials and methods a cross-sectional study was done on a randomly selected sample of 4,636 iranian children who were referred to screening program in 2013 were participated i...

background in 1996, donovan and colleagues represented a scoring system for better prediction of hirschsprung disease (hd). objectives our objective was to devise another scoring system that uses a checklist of radiologic and clinical signs to determine the probability of hd in suspicious patients. patients and methods in a diagnostic accuracy study, 55 children with clinical manifestations of ...

in endemic area the most challenging problem for brucellosis is to find a reliable diagnostic method. in this case-control study, we investigated the accuracy of elisa test for diagnosis of human brucellosis and determined the optimal cut-off value for elisa results in iran. the laboratory diagnosis of brucellosis was performed by blood isolation of brucella organism with a bactec 9240 system a...