نتایج جستجو برای: actin gene

تعداد نتایج: 1174543  

Journal: :American journal of physiology. Cell physiology 1998
Fredrick M Pavalko Neal X Chen Charles H Turner David B Burr Simon Atkinson Yeou-Fang Hsieh Jinya Qiu Randall L Duncan

Mechanical stimulation of bone induces new bone formation in vivo and increases the metabolic activity and gene expression of osteoblasts in culture. We investigated the role of the actin cytoskeleton and actin-membrane interactions in the transmission of mechanical signals leading to altered gene expression in cultured MC3T3-E1 osteoblasts. Application of fluid shear to osteoblasts caused reor...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1984
P Gunning P Ponte L Kedes R Eddy T Shows

We have examined the relationship between chromosomal location and regulation of the two human genes encoding the sarcomeric muscle actins. The human genes encoding skeletal alpha-actin and cardiac alpha-actin are co-expressed in both human skeletal muscle and heart. We have subcloned a single-copy DNA fragment from an intervening sequence in the human cardiac alpha-actin gene and a single-copy...

Journal: :Genetics 2006
Shiro Yoshiuchi Takaharu Yamamoto Hiroshi Sakane Jun Kadota Junko Mochida Masahiro Asaka Kazuma Tanaka

A formin Bni1p nucleates actin to assemble actin cables, which guide the polarized transport of secretory vesicles in budding yeast. We identified mutations that suppressed both the lethality and the excessive actin cable formation caused by overexpression of a truncated Bni1p (BNI1DeltaN). Two recessive mutations, act1-301 in the actin gene and sla2-82 in a gene involved in cortical actin patc...

2016
Amir S. Sharili Fiona N. Kenny Maria K. Vartiainen John T. Connelly

The actin cytoskeleton is a classic biomechanical mediator of cell migration. While it is known that actin also shuttles in and out of the nucleus, its functions within this compartment remain poorly understood. In this study, we investigated how nuclear actin regulates keratinocyte gene expression and cell behavior. Gene expression profiling of normal HaCaT keratinocytes compared to HaCaTs ove...

Journal: :Molecular and cellular biology 1981
R H Scheller L B McAllister W R Crain D S Durica J W Posakony T L Thomas R J Britten E H Davidson

A set of at least 11 actin genes has been isolated from genomic recombinant deoxyribonucleic acid libraries of the sea urchin Strongylocentrotus purpuratus. Most of the isolates derive from a library which represents the genome of a single animal. There are at least five distinct types of sea urchin actin gene, some of which are represented by multiple copies in the genome. The actin gene types...

Journal: :Molecular and cellular biology 1990
T M Dunn D Shortle

Extragenic suppressors of a new temperature-sensitive mutation (act1-4) in the actin gene of Saccharomyces cerevisiae were isolated in an attempt to identify genes whose products interact directly with actin. One suppressor with a cold-sensitive growth phenotype defined the new gene, SAC7, which was mapped, cloned, sequenced, and disrupted. Genetic analysis of strains that are disrupted for SAC...

دارابیان, سیما, رضایی, ساسان, صفری, محمد رضا, کردبچه, پریوش,

Background and Objectivs: Trichophyton rubrum is considered as the most common causes of dermatophytosis in human skin and nail tissues. Microsporeum canis is a zoophile dermatophyte which can be transmited to human. HSP70 is a 70 KD heat shock protein in fungi. In this study, the effects of variable CO2 concentrations were examined on HSP70 expression in T. rubrum and M. canis. Materials and M...

Journal: :FEMS microbiology letters 1995
J Kreft M Dumbsky S Theiss

Within infected eukaryotic cells the two pathogenic Listeria species, L. monocytogenes and L. ivanovii, induce polymerization of cellular actin and the formation of a propulsive actin tail at one bacterial pole. For L. monocytogenes it has been shown that the product of the listerial actA gene is required for this process which is regarded as a model for actin-based motility. We have now cloned...

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