(7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid methyl ester(1) upon reaction with ethyl bromoacetate furnishes (7-ethoxycarbonylmethoxy-2-oxo-2H-chromen-4-yl)-acetic acid methylester (2), which on treatment with 100% hydrazine hydrate yields (7-hydrazinocarbonylmethoxy-2-oxo-2H-chromen-4-yl)-acetic acid hydrazide (3). The condensation of compound 3 with different aromatic aldehydes afforded a se...

Acetobacter suboxydans has a powerful system for the oxidation of ethanol to acetic acid, as might be expected from the fact that the acetic acid bacteria have long been used for the commercial production of vinegar. Alcohol dehydrogenase in soluble extracts has been found to be DPlSspecific1 (1). It has now been observed that either TPN or DPN can be used as coenzyme for the oxidation of aceta...

Kozakia baliensis belongs to the family Acetobacteraceae and was described for the first time in 2002. These acetic acid bacteria are able to produce acetic acid from various carbon sources and 2- and 5-keto-d-gluconate from glucose. The novel K. baliensis strain SR-745 was isolated from a pineapple fruit bought in a German supermarket. The strain produces large amounts of organic acids when gr...

The transcriptional regulator CprK controls the expression of the reductive dehalogenase CprA in organohalide-respiring bacteria. Desulfitobacterium hafniense CprA catalyses the reductive dechlorination of the terminal electron acceptor o-chlorophenol acetic acid, generating the phenol acetic acid product. It has been shown that CprK has ability to distinguish between the chlorinated CprA subst...

Production of microbial cells Baker’s yeast, single cell protein, lactic acid bacteria Production of primary metabolites Ethanol (both in beer and wine production and for technical use), lactic acid, citric acid, acetic acid, amino acids, vitamins Production of secondary metabolites Antibiotics (penicillins, cephalosporins, clavulanic acid, tetracycline), skikonin Production of microbial enzyme...

The new 1,3,4-oxadiazolylquinoxaline ring system was synthesized by the condensation of the quinoxaline 1,4-dioxide acid hydrazide 6 with acetyl chloride in one-pot synthesis. In which the hydrazide was refluxed in excess of acetyl chloride, acetic anhydride or acetic acid in the presence of phosphorus oxychloride forming the 1,3,4-oxadiazolylquinoxaline ring system. Molecular modeling studies ...