Introduction: In patients with thyroid carcinoma, radiation absorbed doses of the thyroid and surrounding tissues is important to weigh risk and benefit considerations. In nuclear medicine, the accuracy of absorbed dose of internally distributed radionuclides is estimated by different methods such as MIRD and direct method using TLD. The aim of this study is using TLD and a phantom to determine...

Abstract Background Patients with metastatic, castration-resistant prostate cancer (mCRPC) present an increased tumor burden in the skeleton. For these patients, Lutetium-177 (Lu-177) radioligand therapy targeting prostate-specific membrane antigen (PSMA) has gained increasing interest promising outcome data. Patient-individualized dosimetry enables improvement of success aim minimizing absorbe...

One factor that is critical to the potential effectiveness of radioimmunotherapy is the design of radiometal-chelated antibodies that will be stable in vivo. Stability in vivo depends on the condition that both the chelate linkage and radiolabeling procedures not alter antibody specificity and biodistribution. In addition, synthesis and selection of the chelating agent is critical for each radi...

The structure of endocrine morbidity is characterized by a significant spread thyroid pathology. insufficient efficacy inorganic iodine drugs poses the problem search for new means deficiency treatment and prevention. Given progressive aging population in economically developed countries, purpose study was to clarify effect organic on features absorption elimination radioactive from glands vari...

Introduction: This study introduces a novel polyvinyl chloride (PVC)/tungsten composites with characterization of their shielding properties by employing different techniques. Methods: The PVC/tungsten composites were produced by employing various weight fractions of tungsten micro-particles including 0, 20, and 40 % wt via melt blending method. In the next st...

In April 1996 the French Ministry of Health decided to distribute stable iodine tablets to the population living in the vicinity of all nuclear power plants (NPP) in France. In case of a severe nuclear accident, the intake of stable iodine would prevent irradiation of the thyroid by the radioactive iodine released by the plant. This preventive distribution began in late 1996 around four pilot s...

UNLABELLED High-throughput deep-sequencing technology has generated an unprecedented number of expressed short sequence reads, presenting not only an opportunity but also a challenge for prediction of novel microRNAs. To verify the existence of candidate microRNAs, we have to show that these short sequences can be processed from candidate pre-microRNAs. However, it is laborious and time consumi...