PurposeThe use of Angiotensin II (ANGII), the most potent endogenous vasopressor, has not been studied in patients with cardiogenic shock on temporary mechanical circulatory support (tMCS). We aimed to evaluate hemodynamic response ANGII adult tMCS and further describe patient characteristics its efficacy.MethodsCardiogenic who were supported by (IABP, Impella, VA-ECMO) received included study....

This study aims to explore police students’ self-rated mental health and physical activity levels the relationship between them. Based on longitudinal cross-sectional data ( N = 722), two scales orientation were developed. The of analyzed using t-test, ANOVA, X 2 . During education, (1) level decreases for men, (2) there is a decline in positive both sexes, (3) women report more negative orient...

This paper proposes a flexible CELP speech coder with bitrate and bandwidth scalabilities for multimedia applications. The coder is based on multi-pulse-based CELP coding and consists of a bitrate scalable base-band coder and a bandwidth extension tool. The bitrate scalable base-band CELP coder employs multi-stage excitation coding based on an embedded-coding approach. The multipulse excitation...

BACKGROUND AND OBJECTIVES Resistance to a wide variety of common antimicrobials has made the proliferation of Extended spectrum β-lactmase (ESBL) producing strains a serious global health concern that has complicated treatment strategies. The high proportion of ESBL producers among the Enterobacteriaceae and the complex molecular epidemiology with diverse types of ESBL genes are alarming. This ...

Focal adhesion kinase (FAK) and focal adhesion kinase-related nonkinase (FRNK) are likely involved in mechanical signaling during hypertension. We investigated expression, subcellular distribution, and phosphorylation of FAK, as well as FRNK in left ventricles of spontaneously hypertensive heart failure rats. Compared with normotensive controls, FAK and FRNK increased in left ventricles of hype...

Proteases regulate numerous biological processes with a degree of specificity often dictated by the amino acid sequence of the substrate cleavage site. To map protease/substrate interactions, a 722-member library of fluorogenic protease substrates of the general format Ac-Ala-X-X-(Arg/Lys)-coumarin was synthesized (X=all natural amino acids except cysteine) and microarrayed with fluorescent cal...

ATP-dependent Lon protease degrades specific short-lived regulatory proteins as well as defective and abnormal proteins in the cell. The crystal structure of the proteolytic domain (P domain) of the Escherichia coli Lon has been solved by single-wavelength anomalous dispersion and refined at 1.75-A resolution. The P domain was obtained by chymotrypsin digestion of the full-length, proteolytical...

Objective To evaluate epidemiological indicators and clinical profile of leprosy patients in Dhaka city. Methods In this cross-sectional observational study 722 new leprosy patients registered in six different clinics of The Leprosy Mission International – Bangladesh, Dhaka program over two and half years (January 2011 to June 2013) were included. Demographic details and clinical characteristic...