Recently the first detections of highly ionised gas associated with two Warm-Hot Intergalactic Medium (WHIM) filaments have been reported. The evidence is based on X-ray absorption lines due to O VII and other ions observed by Chandra towards the bright blazar Mrk 421. We investigate the robustness of this detection by a re-analysis of the original Chandra LETGS spectra, the analysis of a large...

The active galaxy Markarian 421 underwent a substantial outburst in early 2001. Between January and May of that year, the STACEE detector was used to observe the source in γ-rays between the energies of 50 and 500 GeV. These observations represent the lowest energy γ-ray detection of this outburst by a ground-based experiment. Here we present results from these observations, which indicate an a...

(1|1) [1090]. (s, t) [2494]. 1 [299, 421]. 2 [299, 421, 478, 537, 806, 1094, 1134, 1271, 1300, 1373, 1455, 1730, 1797, 1826, 1855, 2023, 2029, 2344]. 3 [251, 299, 314, 691, 768, 1054, 1180, 1197, 1281, 1490, 1601, 1856, 1935, 1979, 2009, 2029, 2344, 2416, 2429, 2435, 2452, 2476, 2517, 2571]. 4 [1639, 1751, 2132]. 5 [299]. 9 [154]. ∗ [1518]. 3 [1482]. RP [669]. A∗ [922]. β [1978]. C [2040]. d [5...

Immunoglobulins (Igs) in uninfected humans recognize residues 421-433 located in the B cell superantigenic site (SAg) of the HIV envelope protein gp120 and catalyze its hydrolysis by a serine protease-like mechanism. The catalytic activity is encoded by germline Ig variable (V) region genes, and is expressed at robust levels by IgMs and IgAs but poorly by IgGs. Mucosal IgAs are highly catalytic...

Synergism of fenvalerate with piperonyl butoxide (PB), NIA-16388 (NIA), S-421, and MGK-264 on both susceptible (S) and fenvalerate-selected (FS) strains of diamondback moth, Plutella xylostella L, were determined in laboratory tests. Further, combinations of fenvalerate and these synergists were tested for their efficacies against resistant strain under field conditions in the Cameron Highlands...

BACKGROUND Ataxia telangiectasia-mutated (ATM) gene downexpression has been reported in sporadic breast carcinomas (BC); however, the prognostic value and mechanisms of ATM deregulation remain unclear. PATIENTS AND METHODS ATM and miRNAs (miR-26a, miR-26b, miR-203, miR-421, miR-664, miR-576-5p and miR-18a) expression levels were evaluated by quantitative real-time PCR (RT-qPCR) in 52 BC and 3...

Kumru H, Benito J, Murillo N, et al. Effects of high-frequency repetitive transcranial magnetic stimulation on motor and gait improvement in incomplete spinal cord injury patients. Neurorehabil & Neural Repair 2013;27:421-429. Original DOI: 10.1177/1545968312471901.

We present the results of a detailed temporal analysis of the bright BL Lac object Mrk 421 using the three available long timing mode observations by the EPIC PN camera. This detector mode is characterized by its long life time and is largely free of photon pile-up problems. The source was found in different intensity and variability states differing by up to more than a factor of three in coun...