This work investigated the toxicity of inorganic mercury and zinc preventive effects in female rats sacrificed 12 or 48 h after HgCl2 exposure. Female Wistar rats were subcutaneously injected with ZnCl2 (27 mg/kg) or saline (0.9 %), and 24 h later they were exposed to HgCl2 (5 mg/kg) or saline (0.9 %). Rats sacrificed 12 hours after Hg administration presented an increase in kidney weight and a...

Glutamatergic neurons contain free zinc packaged into neurotransmitter-loaded synaptic vesicles. Upon neuronal activation, the vesicular contents are released into the synaptic space, whereby the zinc modulates activity of postsynaptic neurons though interactions with receptors, transporters and exchangers. However, high extracellular concentrations of zinc trigger seizures and are neurotoxic i...

Ultraviolet (UV) radiation is known to cause oxidative stress, inflammation, DNA damage and apoptotic cell death; however, many details of these malign mechanism have yet to be elucidated. In this study, the exposure of adult human epidermal keratinocytes (HEKa) with UVB (>100 mJ/cm(2)) resulted in the significant increase of intracellular zinc that was released from its storage and was detecte...

this study was conducted to determine the spatial variability and mapping of available micronutrients iron, zinc, copper and manganese on 20,000 hectares of soils in south of tehran lands in order to identify deficiency, enough and toxicity areas. 196 surface soil samples (0-25cm) to a regular grid network of 1000×1000m were collected and extracted by dtpa and tea and concentrations of elements...

chemical pollutants presence in water may induce severe ecological consequences and consequently affecting aquatic ecosystems integrity. heavy metals are dangerous pollutants for aquatic inhabitants that have a great stability. heavy metals contamination (pollution) of the surface waters happens widely by discharge of mill effluents. the objective of the present study was to determine the 50% l...

The toxic effects of the metals cadmium, zinc and copper on microbial activity in the activated sludge process, are reported. The dissolved metals were added to the process in synthetic wastewater with a COD of 520 mg L. Metal toxicity was determined by the reduction in activity levels of variables such as the specific oxygen uptake rate and mass fraction of active cells present in the reactor....

Sources Of Copper .........................................................................................................................1 Environmental Copper...............................................................................................................1 Copper Water Pipes ...........................................................................................................

A case history of acute copper toxicity in a flock of Garole sheep has been presented. The animals which suffered from the toxicity were fed solely on leaves of mahogany plant for two days prior to the onset of the symptoms. The soil in the region of West Bengal is deficient in both zinc and molybdenum, which may have caused copper imbalance in the animals. Serum biochemical and postmortem find...

Zinc exposure is receiving increasing attention as a public health problem because of the U-shaped dose-response curve in which adverse health effects are associated with the presence of either too little or too much zinc in the vulnerable tissues or organs. The growing scientific interest and research have led to a paradigm shift in terms of which arm of the U-curve should be of most concern t...

This review critically summarizes the literature on the spectrum of health effects of zinc status, ranging from symptoms of zinc deficiency to excess exposure. Studies on zinc intake are reviewed in relation to optimum requirements as a function of age and sex. Current knowledge on the biochemical properties of zinc which are critical to the essential role of this metal in biological systems is...