نتایج جستجو برای: vibrio cholera
تعداد نتایج: 23857 فیلتر نتایج به سال:
Between 1951 and 1959, Sambhu Nath De made crucial discoveries on the pathogenesis of cholera that changed the course of our understanding of the disease. The discovery that cholera is caused by a potent exotoxin (cholera enterotoxin) affecting intestinal permeability, the demonstration that bacteria-free culture filtrates of Vibrio cholerae were enterotoxic, and the development of a reproducib...
In 2012, Sierra Leone experienced its worst cholera outbreak in over 15 years affecting 12 of the country's 13 districts. With limited diagnostic capability, particularly in bacterial culture, the cholera outbreak was initially confirmed by microbiological testing of clinical specimens outside of Sierra Leone. During 2012 - 2013, in direct response to the lack of diagnostic microbiology facilit...
Although there are many records 01 the finding of vibrios in the stools of healthy individuals, there is no means of establishing whether the strains isolated were those conforming to the vibrio now generally accepted as Vibrio cholerce. Recent work on the antigenic structure of vibrios has shown that V. cholerce possesses a specific ' 0 ' antigen and that the thermo-labile ' H ' antigen is sha...
cases which in general symptomatology and clinical features could not be distinguished from cases of true cholera confirmed by laboratory findings. But when the stools of such cases were examined bacteriologically they gave persistently negative results and thus stood in marked contrast to another group of cases investigated in the same field almost about the same time. In the latter group Koch...
This review highlighted the following: (i) pathogenic mechanism of the thermostable direct hemolysin produced by Vibrio parahaemolyticus, especially on its cardiotoxicity, (ii) heat-labile and heat-stable enterotoxins produced by enterotoxigenic Escherichia coli, especially structure-activity relationship of heat-stable enterotoxin, (iii) RNA N-glycosidase activity of Vero toxins (VT1 and VT2) ...
Cholera causes significant morbidity and mortality worldwide. For travelers, the risk of developing cholera per month of stay in a developing country is approximately 0.001%-0.01%, and cholera may present as traveler's diarrhea. In the United States, only a poorly tolerated, marginally effective, parenterally administered, phenol-inactivated vaccine is available. Outside the United States, 2 ad...
abstract background and purpose:cholera is an endemic disease in iran and in some cases each year from around the country report. the aim of this study was to evaluate the prevalence of the disease cholera among people suffering from acute diarrhea in the aranvabidgol. materials and methods:in this study, patients with acute diarrhea were examined for cholera detection in the city of aranvabidg...
Plasmid profiles, the location of cholera toxin subunit A genes, and the presence of the defective VcA1 prophage genome in classical Vibrio cholerae isolated from patients in Bangladesh in 1982 were compared with those in older classical strains isolated during the sixth pandemic and with those in selected eltor and nontoxigenic O1 isolates. Classical strains typically had two plasmids (21 and ...
BACKGROUND Vibrio cholerae is a human intestinal pathogen and V. cholerae of the O139 serogroups are responsible for the current epidemic cholera in China. In this work, we reported the whole genome sequencing of a V. cholerae O139 strain E306 isolated from a cholera patient in the 306th Hospital of PLA, Beijing, China. RESULTS We obtained the draft genome of V. cholerae O139 strain E306 with...
A non-pathogenic "indicator" organism to relapse Vibrio cholerae in the routine quality control of TCBS medium was sought among a large collection of freeze-dried vibrios isolated mostly from environmental sources. One strain, which was consistently more sensitive to inhibition of growth on TCBS medium that strains of V. cholerae and V. parahaemolyticus, is recommended for this purpose. It has ...
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