The article provides an overview of modern data on the main gel bases used in technology semisolid dosage forms. classes gelling substances are characterized. According to data, choice excipient must be justified from point view physicochemical properties active substance, and depends place application gel.

background: at the present time, teaching pharmacology for medical students mainly focuses on the basic principles of pharmacology. this study was conducted to assess the current situation of pharmacology teaching and the necessity of developing clinical pharmacology from the viewpoint of medical interns and externs in tabriz university of medical sciences. methods: this descriptive cross-secti...

BACKGROUND The ethical, methodological, and technical aspects of pediatric research, often results in complications and delays in implementation. Our objective was to identify factors associated with the implementation duration of hospital-based pediatric studies. METHODS All hospital-based pediatric studies sponsored by AP-HP between 2002 and 2008 were retrospectively identified. Association...

Tablet is the most popular among all dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; however in many cases immediate onset of action is required than conventional therapy. To overcome these drawbacks, immediate release pharmaceutical dosage form has emerged as alternative oral dosage forms. There are novel types of dosage forms ...

Background: Cesarean delivery has become the most common major surgical procedure in many parts of the world. Induction of labor in women with prior cesarean delivery is an alternative to mitigate the rising cesarean rates. Objectives: To compare the VBAC success rate between two vaginal forms of dinoprostone for labor induction in women with prior cesarean section. Material and Methods: A pilo...

Gastroretentive dosage forms (GRDF) has received significant interest in the past few decades as they can improve the limitation of most conventional and oral controlled release drug delivery system related to fast gastric-emptying time. An optimum GRDF system can be defined as a system which retains in the stomach for a sufficient time interval against all the physiological barriers, releases ...

Biotechnology is now contributing almost one third of new drugs, and the trend is expected to be similar based on the number of molecules in different clinical trials. Most of these protein based pharmaceuticals are delivered by injections, which are painful and carries a risk of infection. Alternative delivery routes/techniques are being investigated and transdermal iontophoresis is one of the...