Aquagenic urticaria (AQ) is a rare physical urticaria induced by contact with water. It may be distinctive clinically, evident as 1-2 mm folliculopapular urticaria, a pattern also characteristic of cholinergic urticaria. AQ has a truncal and upper extremity distribution within 20-30 minutes after contact with water, regardless of its temperature or source. AQ is usually symptomatic with mild to...

Chronic urticaria has long been thought to be associated with autoimmune conditions, in particular autoimmune thyroid disease (AITD). We detail an unusual case of a 49-year-old patient presenting with urticaria distributed on both shins and hands, with no known associated triggers, and subsequently diagnosed with AITD. The urticaria resolved upon treatment of the AITD. We also summarize the cur...

Objective: To compare the efficacy of autologous serum with Antihistamine therapy in treating chronic urticaria.
 Study Design: Quasi-experimental study.
 Place and Duration Study: Dermatology Department, Pak Emirate Military Hospital, Rawalpindi Pakistan, from Jul 2018 to Jan 2019.
 Methodology: One hundred four patients urticaria (≥3 times/ week for ≥6 weeks) ages ranging 16 70...

We report a case of chronic idiopathic urticaria associated with nodular goiter and Graves disease. The urticaria resolved with normalization of the thyroid function.

INTRODUCTION The basophil activation test showing CD63 up regulation could be a specific and sensitive in vitro complementary text to the in vivo autologous serum skin test for the activity assessment of the patients suffering autoimmune chronic spontaneous urticaria. The aim of this study is to define the basophil activation test as a useful tool in clinical practice in order to identify those...

BACKGROUND Previous success rates of psoralen and ultraviolet A (PUVA) and narrowband UVB (NB-UVB) in the treatment of chronic urticaria are reported in few studies with no previous reports on the comparable efficacy of both modalities in the disease. AIM We aimed to compare the efficacy of PUVA versus NB-UVB in the treatment of chronic urticaria. METHODS Twenty-four patients with chronic u...

Introduction Predominantly neutrophilic inflammatory infiltrates are seen in a subset of chronic urticaria patients, with lesions that tend to be less itchy and poorly responsive to antihistamine therapy.[1,2] There have been reports of patients with neutrophilic dermatoses presenting with extracutaneous inflammation.[3] We present two patients with neutrophilic urticaria and extracutaneous sym...

Twenty-three children with chronic urticaria were treated with an elimination diet for two weeks. Eighteen completed the period of dietary elimination; in seven of the 18 children there was a marked remission of the urticaria during the second week of the diet. The administration of challenge capsules provoked an exacerbation of urticaria in five of the 14 (36%) children given aspirin. The inci...

I Chronic idiopathic urticaria (CIU) is the most frequent form of urticaria, accounting for 70-80% of the cases (1). CIU is defined as a 6-week or longer history of urticaria in the absence of detectable physical, allergic, vasculitic, infectious or drug-induced causes (2). The presence of autoantibodies directed toward IgE or to the high-affinity IgE Fc receptor, detected by intradermal test w...

ma are cutaneous manifestations of localized edema. They are common skin diseases that typically result from the same pathophysiologic processes. The primary difference between the disorders is that urticaria is associated with localized edema involving the upper dermis, whereas angioedema is associated with localized edema involving deeper layers of the skin, as well as subcutaneous and submuc...