نتایج جستجو برای: unilateral chronic renal obstruction
تعداد نتایج: 779273 فیلتر نتایج به سال:
BACKGROUND/AIMS Unilateral ureteral obstruction (UUO) results in renal injury. Studies report increased injury indices in male rats following UUO. Our study examined whether this gender-based renal response to UUO was reflected in sustained differences following relief of obstruction. METHODS Adult male/female rats (200-400 g) were subjected to either sham surgery (S/RN) or UUO (UUO/RN). At 2...
Progressive renal fibrosis in chronic kidney disease (CKD) greatly contributes to end-stage renal failure and is associated with high mortality. The identification of renal fibrosis biomarkers for the diagnosis and the monitoring of disease progression in CKD is urgently needed. Whole-transcriptomic analysis of renal tissues in a unilateral ureteral obstruction (UUO) mouse model revealed that t...
Renal insufficiency as a result of congenital obstructive nephropathy is a consequence of impaired renal growth: chronic unilateral ureteral obstruction (UUO) results in greater injury to the immature kidney than to the adult kidney. The neonatal kidney responds to UUO by marked activation of the renin-angiotensin system, which contributes to severe vasoconstriction and progressive interstitial...
Abstract Background and Aims Our previous studies have shown that angiogenic growth factors are dysregulated in fibrotic kidneys. In murine models of progressive renal disease, angiopoietin-2 (Angpt2) was upregulated injured tubule epithelial cells. We hypothesize overexpression Angpt2 cells would exacerbate fibrosis inflammation. Method The unilateral ureteral obstruction (UUO) ischemia-reperf...
Bachground: Unilateral obstructions of ureter either due to extramural, or intramural, and or intraluminal lead to unilateral hydronephrosis. Ureteral obstruction, partial or complete, produces a progressive disease in excretory functions of the kidneys with subsequent destruction of renal parenchyma. Material and Methods: 30 cases of unilateral hydronephrosis who fulfilled the inclusion and ex...
introduction: osteodystrophy is one of the long term complications of chronic renal failure and is expressed in two formslow turn over and high turn over. it is an important cause of morbidity in patients with renal failure and if diagnosed and managed properly, many problems of these patients can be resolved. in this study we evaluated the prevalence of hyperparathyroidism in hemodialysis pati...
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