نتایج جستجو برای: type carbapenemases

تعداد نتایج: 1342660  

Journal: :Antimicrobial Agents and Chemotherapy 2014

2016
María Soledad Ramirez Gang Xie German M. Traglia Shannon L. Johnson Karen W. Davenport David van Duin Azam Ramazani Federico Perez Michael R. Jacobs David J. Sherratt Robert A. Bonomo Patrick S.G. Chain Marcelo E. Tolmasky

Klebsiella pneumoniae has become one of the most dangerous causative agents of hospital infections due to the acquisition of resistance to carbapenems, one of the last resort families of antibiotics. Resistance is usually mediated by carbapenemases coded for by different classes of genes. A prolonged outbreak of carbapenem-resistant K. pneumoniae infections has been recently described in northe...

Journal: :Diagnostic Microbiology and Infectious Disease 2021

We investigated the presence of carbapenemases in carbapenem-resistant Pseudomonas aeruginosa isolates, which were collected over a 14-month period Turkish hospital, with in-depth molecular characterization carbapenemase-producing isolates. Among 45 study 2 isolates identified as carbapenemase producers by both Carba NP and Carbapenem Inactivation Method tests, only 1 them gave positive result ...

Journal: :Acta Biomedica Scientifica (East Siberian Biomedical Journal) 2021

Journal: :Journal of clinical and diagnostic research : JCDR 2014
Parisa Vali Fereshteh Shahcheraghi Maryam Seyfipour Maryam Alsadat Zamani Mohammad Reza Allahyar Mohammad Mehdi Feizabadi

BACKGROUND Cystic Fibrosis (CF) is an autosomal recessive genetic disorder in white populations caused by mutation in a gene that encodes Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. Since frequent respiratory tract infections are the major problem in patients with CF, obligation to identify the causative bacteria and determining their antibiotic resistance pattern is cru...

Journal: :Antimicrobial agents and chemotherapy 2009
Jason W Bennett Monica L Herrera James S Lewis Brian W Wickes James H Jorgensen

Carbapenemases are among the newest resistance mechanisms to emerge in some gram-negative bacteria. We describe bacteremia in a critically ill liver transplant recipient infected with KPC-2-producing Enterobacter cloacae and Pseudomonas putida. Although this enzyme has been previously described in Enterobacter spp., this is the first report of KPC carbapenemase in P. putida.

2014
MARIA BĂLĂŞOIU A.T. BĂLĂŞOIU RODICA MĂNESCU CARMEN AVRAMESCU OANA IONETE

Pseudomonas aeruginosa genus bacteria are well known for their increased drug resistance (phenotypic ang genotypic resistance). The most important resistance mechanisms are: enzyme production, reduction of pore expression, reduction of the external membrane proteins expression, efflux systems, topoisomerase mutations. These mechanisms often accumulate and lead to multidrug ressitance strains em...

2014
P. Maureen Cassidy Christopher Pfeiffer Genevieve L. Buser Zintars G. Beldavs

Background. Preventing the spread of carbapenem-resistant Enterobacteriaceae (CRE) is important to public health because of high infection-related morbidity, mortality, and cost. Carbapenemase producing (CP)-CRE are most concerning because of their rapid global dissemination. In 2013, CRE in Oregon were defined as Enterobacteriaceae with non-susceptibility to ≥1 carbapenem, including ertapenem,...

Journal: :The Journal of antimicrobial chemotherapy 2014
Anu Jain Katie L Hopkins Jane Turton Michel Doumith Robert Hill Richard Loy Daniele Meunier Rachel Pike David M Livermore Neil Woodford

OBJECTIVES Gram-negative bacteria with diverse carbapenemases, including New Delhi metallo-β-lactamase (NDM) enzymes, have been increasingly recorded in the UK since 2007. We analysed patient data for NDM-positive isolates confirmed by the national reference laboratory from UK laboratories from February 2008 to July 2013. METHODS Isolates resistant to carbapenems and with imipenem MICs reduce...

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