Herein, we described the first case of self-inoculation in a veterinarian with bovine Johne’s disease(BJD) attenuated vaccine in Iran that required medical attention. A needle-stick injury to the right thumb of ayoung veterinarian during vaccination of cattle with BJD vaccine resulted in an inflammation that not onlyfailed to resolve but also progressed to a lesion 2.5 cm in diameter. The usual...

One hundred and twenty Brazilian patients with several forms of hanseniasis were tested with DNCB. The results were the following: 1) the sensitization of patients with hanseniasis to DNCB was lower than that seen in the general population; 2) the sensitization of the borderline and virchowian forms of hanseniasis were lower than that seen in the indeterminate and tuberculoid forms.

BACKGROUND Lepromatous leprosy caused by Mycobacterium leprae is associated with antigen specific T cell unresponsiveness/anergy whose underlying mechanisms are not fully defined. We investigated the role of CD25(+)FOXP3(+) regulatory T cells in both skin lesions and M.leprae stimulated PBMC cultures of 28 each of freshly diagnosed patients with borderline tuberculoid (BT) and lepromatous lepro...

Nodular leprosy of childhood (NL) is a benign clinical variant of tuberculoid leprosy that affects breast-feeding infants and children that remained in a highly infected environment. The lesions resolve with complete healing and NL has been considered a manifestation of allergy and congenital immunity to Mycobacteria leprae. We studied the tissue reaction, Mycobacterial antigen frequency, and t...

The so-called nerve abscess, one of the interesting features of leprosy, is recognized to be neither common nor rare in the neural and tuberculoid forms of the disease. On the other hand the condition is exceptional and rare in lepromatous leprosy, but it does occur although there are very few reports of it. Some workers, e. g., Hughes (5), have held that nerve abscess occurs only in tuberculoi...