septic arthritis with polyarticular presentation is an uncommon clinical entity. a case of complicated staphylococcal infection with purulent and reactive polyarthritis, osteomyelitis, cutaneous and pleuropericardial involvement as well as transient blindness is presented here.

toxic shock syndrome in children following infection with influenza is a very rare syndrome. if it is not diagnosed quickly, it may cause significant morbidity and mortality. for diagnosis of toxic shock syndrome, clinical and laboratory criteria are used. our patient is a 3.5-year old boy who admitted to the hospital with high fever, weakness, toxicity, hypotension and skin rash due to influen...

toxic optic neuropathy (ton) is a group of medical disorders which can be defined by visual impairment due to optic nerve damage by a toxin. the exposure to a toxic substance can occur at the workplace, with ingestion of materials/ foods containing a toxin, or the use of systemic medications. ton is a disease entity which is not only under-diagnosed, but also often diagnosed at a stage when rec...

conclusions the nps-induced ots may increase the pro-inflammatory responses. on the other hand, administration of antioxidants such as nac and vitamin c and e prior to exposure to metal nps significantly decreases ots conditions. evidence acquisition here, a nanotechnology approach is evaluated using nps in human neuronal protection against ots. it may be wide therapeutic applications in the ca...

objective: zayandehrood habitat has economical and environmental importance in central plateau of iran    and it performs a vital role for habitants, agriculture section and the industries which are located along river bed. so current research  has been done to measure the contamination of heavy metals, its changes along the river route and defining the important and effective regions on this c...

Constituents of coal combustion waste (CCW) expose aquatic organisms to complex mixtures of potentially toxic metals and metalloids. Multi-element trace element analyses were used to distinguish patterns of accumulation among 8 genera of dragonfly nymphs collected from two sites on a CCW contaminated coastal plain stream. Dragonfly nymphs are exceptional for comparing trace element accumulation...

The use of the term “heavy metal” is regularly questioned by scientific community. Here, we followed evolution (1970–2020) in number published papers including this their title. Thus, can evidence a continuous, albeit sometimes stabilizing, increase especially environmental journals. After several other warning opinions, propose that it should be replaced literature terms like “metal”, “metallo...

background : due to the importance of the metal zinc as an essential biological element with known toxic properties, and considering the widespread secondary infections caused by pseudomonas aeruginosa strains with resistance to antibiotics and disinfectants, the present study aimed at exploring the antimicrobial properties of the metal zinc in both clinical and environmental multiple drug resi...

BACKGROUND Evolvability is an intrinsic feature of all living cells. However, newly emerging, evolved features can be undesirable when genetic circuits, designed and fabricated by rational, synthetic biological approaches, are installed in the cell. Streamlined-genome E. coli MDS42 is free of mutation-generating IS elements, and can serve as a host with reduced evolutionary potential. RESULTS...

AIMS We have shown previously that non-toxic inhibition of the ubiquitin-proteasome system upregulates antioxidative defence mechanisms and protects endothelial cells from oxidative stress. Here, we have addressed the question whether the induction of antioxidative enzymes contributes to cardioprotection by non-toxic proteasome inhibition. METHODS AND RESULTS Treatment with 0.5 micromol/L MG1...