background: during pregnancy and lactation outstanding changes occur in mother’s vitamin d metabolism. this study was carried out to evaluate the efficacy of 300,000 iu vitamin d given intramuscularly on body status in new cases of gestational diabetes mellitus (gdm). methods: this is a randomized clinical trial with the follow-up period of 3 months. totally 45 participants were randomly divide...

The Pellucid project is developing an adaptable and customisable platform for enabling experience management in public organisations. Starting with a study of the three pilot applications, a uniform framework has been developed for experience management, based on the generation of ‘active hints’ that are presented to the user according to working context. Working context encompasses both positi...

Immunoglobulin (Ig) class switch recombination (CSR) is the process occurring in mature B cells that diversifies effector component of antibody responses. CSR initiated by activity cell-specific enzyme activation-induced cytidine deaminase (AID), which leads to formation programmed DNA double-strand breaks (DSBs) at Ig heavy chain (Igh) locus. Mature use a multilayered and complex regula...

A reverse hemolytic plaque-forming cell (PFC) assay for the enumeration of immunoglobulin-(Ig)secreting cells in nonimmunized rabbits was developed by using erythrocytes coated with anti-Ig antibody. These indicator cells lysed after reacting with the secreted Ig antigen and complement. The anti-Ig antibodies used were specific for the b4 or b5 allotypic specificities, which are antigenic deter...

objective(s) the aim of this study was to evaluate the expressions of two angiogenic immune-markers (cd-31 and vegf), and one proliferative immune-marker (ki-67) in oral pyogenic granulomas (pg), hemangiomas (hem) and inflammatory gingivitis (ig). materials and methods sixty cases of pg, hem and ig (twenty cases each) were examined. immunohistochemical (ihc) staining was performed based on rout...

In vivo Ig responses to soluble, haptenated polysaccharide (PS) Ags are T cell independent and do not require CD40 ligand (CD40L). However, little is known regarding the regulation of in vivo PS-specific Ig responses to intact bacteria. We immunized mice with a nonencapsulated, type 2 Streptococcus pneumoniae (R36A) and compared the parameters that regulated in vivo Ig isotype responses to the ...

Immunoglobulins (Ig) on cells of the immune system: The cytotoxicity test, with class-specific and type-specific anti-Ig sera, identifies kappa and micro determinants on mouse lymphocytes. The proportion of kappa(+) cells is characteristic for each source of cells: 30% of bone marrow cells, 40% of cells from peripheral lymph nodes, 45% of lymphocytes from peripheral blood or peritoneal cavity, ...