Homologous sequences usually have the same, or very similar, functions, so new sequences can be reliably assigned functions if homologous sequences with known functions can be identified. Homology is inferred based on sequence similarity, and many methods have been developed to identify sequences that have statistically significant similarity. This unit provides an overview of some of the basic...

Abstract This paper provides a convenient and practical method to compute the homology intersection pairing of branched double cover 4-ball. To projections links in 3-ball, surfaces 4-ball into boundary sphere, we associate sequence groups, called disoriented homology. We show that is isomorphic link or surface. define on first group surface this equal cover. These results generalize work Gordo...

An enterovirus 71 (EV71) strain Query was isolated from a patient specimen in 2015. In order to known about its genetic evolution, this study amplified gene fragment of the isolated stain by RT-PCT and carried out sequencing of the total genome. The homology and genetic evolution of the gene sequence of the virus strain in the study were analyzed. The results showed that the isolated EV71 strai...

We introduce a method for associating chain complex to module over combinatorial category, such that if the is exact then has rational Hilbert series. prove homology--vanishing theorems these complexes several categories including: category of finite sets and injections, opposite surjections, dimensional vector spaces field injections. Our main applications are modules known as $FS^{op}$ module...

a 5\m='\-incompleteopen reading frame of 525 base pairs. The 3\m='\-untranslatedregion of 946 base pairs contains a repetitive DNA element of the rodent B1 family just between two canonical polyadenylation signals AATAAA, upstream of the poly(A) track. The deduced amino acid sequence for the Mr 24 000 proteins reveals significant homologies of 66\m=.\6,66, 65\m=.\2,63\m=.\1 and 64\m=.\5%with mo...

Studies of hybridization between fowl adenovirus type 1 (chicken embryo lethal orphan virus) DNA and human adenovirus type 2 DNA revealed two short but distinct regions which cross-hybridized under stringent conditions. One of the homologous regions was located between map positions 18.1 and 19.3 and did not correspond to any gene recognized so far. The second region mapped in the hexon gene be...

Sequence alignment and database searching are essential tools in biology because a protein's function can often be inferred from homologous proteins. Standard sequence comparison methods use substitution matrices to find the alignment with the best sum of similarity scores between aligned residues. These similarity scores do not take the local sequence context into account. Here, we present an ...

Sulfate-reducing bacteria (SRB) are anaerobic that form biofilm and induce corrosion on various material surfaces. The quorum sensing (QS) system employs acyl homoserine lactone (AHL)-type QS molecules primarily govern formation. Studies SRB have reported the presence of AHL, but no AHL synthase been annotated in so far. In this computational study, we used a combination data mining, multiple s...