BACKGROUND Cardiopulmonary resuscitation (CPR) and electrical defibrillation are the primary treatment options for ventricular fibrillation (VF). While recent studies have shown that providing CPR prior to defibrillation may improve outcomes, the effects of CPR quality remain unclear. Specifically, the clinical effects of compression depth and pauses in chest compression prior to defibrillation...

We review our recent experimental and modeling results on how cerebellar Purkinje cells encode information in their simple spike trains and present a theory of the function of pauses and regular spiking patterns. The regular spiking patterns were discovered in extracellular recordings of simple spikes in awake and anesthetized rodents, where it was shown that more than half of the spontaneous a...

There is a large body of research on discourse production in Alzheimer's disease (AD). Some studies have focused on pause production, revealing that patients make extensive use of pauses during speech. This has been attributed to lexical retrieval difficulties, but pausing may also reflect other forms of cognitive impairment as it increases with cognitive load. The aim of the present study was ...

Microtubule-based transport is critical for trafficking of organelles, organization of endomembranes, and mitosis. The driving force for microtubule-based transport is provided by microtubule motors, which move organelles specifically to the plus or minus ends of the microtubules. Motor proteins of opposite polarities are bound to the surface of the same cargo organelle. Transport of organelles...

In this study, pauses within speakers’ turns are described and analysed. Tentative results show that different pauses within a speaker’s turn might differ in length. Pause length variations over time in dialogues were investigated, and in 5 out of 6 dialogues, a statistically significant correlation was found between the speakers’ variations in pause length.

This study investigated the ways in which segmental durations co-vary across speakers in a large speech corpus. We found that pauses were negatively correlated with other phones. Speakers who produced longer speech phones tended to have shorter pauses. The approximants had little correlation with the other phone classes. This suggests that the durations of the approximants are controlled by spe...