Since 2013, New Zealand’s regulatory agencies have had a statutory obligation to carry out stewardship. They been expected adopt whole-of-system, life cycle view of regulation, and take proactive collaborative approach the monitoring care system(s) for which they responsibilities. In 2021, after eight years, not managed operationalise their shared stewardship obligations in coherent consistent ...

in mammals, the intrauterine condition has an important role in the development of fetal physiological systems in later life. suboptimal maternal environment can alter the regulatory pathways that determine the normal development of the fetus in utero, which in post-natal life may render the individual more susceptible to cardiovascular or metabolic adult-life diseases. changes in the intrauter...

Background The unregulated availability and irrational use of tuberculosis (TB) medicines is a major issue of public health concern globally. Governments of many low- and middle-income countries (LMICs) have committed to regulating the quality and availability of TB medicines, but with variable success. Regulation of TB medicines remains an intractable challenge in many settings, but the reason...