Aneuploidy in pregnancy is known to increase with advanced maternal age (AMA) and associate with repeated implantation failure (RIF), and repeated miscarriage (RM). Preimplantation genetic screening (PGS) has been introduced into clinical practice, screening, and eliminating aneuploidy embryos, which can improve the chance of conceptions for infertility cases with poor prognosis. These patients...

Objective : To determine whether women with factor V Leiden mutation, a common inherited defect of coagulation, are at increased risk for recurrent pregnancy loss after ICSI. Patients and Methods : Women with recurrent implantation failure were compared to a matching group of women conceived naturally. Factor V Leiden was investigated in each group to determine its homozygosity or heterozygosit...

background: implantation failure is the most important cause of recurrent in vitro fertilization/intra cytoplasmic sperm injection (ivf/icsi) failure. several reports suggest that intercourse during the peritransfer period might improve pregnancy rates. this study is designed to determine whether intercourse during the peritransfer period will improve pregnancy and implantation rates in patient...

BACKGROUND In all IVF programmes, some patients fail to achieve an ongoing pregnancy, even after numerous embryo transfer procedures. An unfavourable environment within the uterus might be a contributory factor to such recurrent implantation failure. This question was addressed by measuring cytokine concentrations and matrix metalloproteinase activities in fluid derived from uterine irrigation ...

Background Recurrent miscarriage (RM) is a frequent condition affecting about 1–3 % of couples and one the most frustrating difficult areas in reproductive medicine since etiology often unknown evidence-based diagnosis treatment strategies are scarce. Likewise, recurrent implantation failure (RIF) considered after at least 3 unsuccessful transfers good quality embryos, remains unexplained 45 in...

background: implantation failure is one of the most important factors limiting success in ivf treatment. the majority of trials have demonstrated favorable effect of endometrial injury on implantation success rate especially in women with recurrent implantation failure, while some studies failed to detect any benefit. objective: the purpose of our trial was to explore whether endometrial injury...