Objective and background: Tumor lysis syndrome (TLS) is a life-threatening emergency demands care of effective outcome with minimal or no side effects. The Hypouricemic agents, including Rasburicase, Allopurinol Febuxostate used for the management TLS. This study was designed to evaluate Role agents by analyzing TLS development rate, control uric acid, Creatinine levels.
 Methods: An exten...

Background: Tumor lysis syndrome caused by widespread tumor cell damage may lead to electrolyte imbalances and express as metabolic disturbance causing clinical abnormalities. Patients and Methods: All patients younger than 16 years with documented malignancy candidate for chemotherapy, in Hamedan province of Iran were enrolled. Results: Out of 69 cancer patients the laboratory form of tumor ...