Colchicine as a vascular disrupting agent creates microtubule destabilization whichinduces vessel blockage and consequently cell death. Accordingly, colchicines and itsanalogues radiolabeled with 99mTc may have potential for visualization of tumor. In this work,deacetylcolchicine a colchicine analogue was labeled with 99mTc via tricine as a coligandand characterized for its tumor targeting prop...

Abstract Dual particle imaging, in which both neutrons and gamma-rays the environment can be individually characterized, is particularly attractive for monitoring mixed radiation emitters such as special nuclear materials (SNM). Effective SNM localization detection benefits from high instrument sensitivity so that real-time imaging or with a limited number of acquired events enabled. For portab...

background: in this study, quantitative 32p bremsstrahlung planar and spect imaging and consequent dose assessment were carried out as a comprehensive phantom study to define an appropriate method for accurate dosimetry in clinical practice. materials and methods: ct, planar and spect bremsstrahlung images of jaszczak phantom containing a known activity of 32p were acquired. in addition, phanto...

A position sensitive detector for 9 MeV gamma rays has been developed as part of a contraband detection system for airports. The system images contraband, such as explosives or drugs, in a geometry similar to medical x-ray computed tomography. A point source of gamma rays shines through an unknown object. Transmission projections of the areal density of detected gamma rays are reconstructed int...