Sindrom pernapasan akut parah coronavirus-2 (SARS-CoV-2) yang menyebabkan pandemi penyakit infeksi COVID-19 menggunakan protein spike untuk dapat berikatan dengan reseptor angiotensin-converting enzyme 2 (ACE2) dalam sel inang . Beberapa kandidat obat diprediksi digunakan terapi seperti, tegobuvir, sonidegib, siramesine, antrafenine, bemcentinib, itacitinib, dan ftalosianina secara farmakologis...

the cornell net carbohydrate and protein system (cncps) model has recently been increasingly employed in preparation of balanced feed ration of dairy cattle in iran. however, a lack of appropriate characterization of the feeds has restricted the model's application. this study was conducted to evaluate the protein contents of some feedstuffs (wheat bran, sugar beet pulp, soybean meal, cott...

We have analyzed the translocation of hepatitis B virus (HBV) precore (PC) proteins by using Xenopus oocytes injected with a synthetic PC mRNA. The PC region is a 29-amino-acid sequence that precedes the 21.5-kDa HBV capsid or core (C) protein (p21.5) and directs the secretion of core-related proteins. The first 19 PC amino acids provide a signal peptide that is cleaved with the resultant trans...

OBJECTIVE The interaction of protein C (PC) with the endothelial PC receptor (EPCR) enhances activated PC generation. We performed targeted gene sequencing of the PC gene (PROC) and EPCR genes (PROCR) in patients with unprovoked venous thromboembolism (VTE) to determine whether mutations that impair PC-EPCR interactions are associated with an increased risk of VTE. APPROACH AND RESULTS We seq...

The protein C (PC) pathway plays an important role in coagulation and inflammation. Many components of the PC pathway have been identified in epidermal keratinocytes, including endothelial protein C receptor (EPCR), which is the specific receptor for PC/activated PC (APC), but the core member of this pathway, PC, and its function in keratinocytes has not been defined. In this study, we reveal t...

In this paper, we have constructed a large scale ATM-connected PC cluster consists of 100 PCs, implemented a data mining application, and optimized its execution environment. Default parameters of TCP retransmission mechanism cannot provide good performance for data mining application, since a lot of collisions occur in the case of all-to-all multicasting in the large scale PC cluster. Using a ...

The protein responsible for both nucleotide pyrophosphatase (EC 3.6.1.9) and alkaline phosphodiesterase I (EC 3.1.4.1) activities was purified from MOPC 315 plasmacytoma cells. A single SDS/PAGE-purified 115-kDa protein band was used to produce a rabbit polyclonal antiserum. This antibody preparation precipitated alkaline phosphodiesterase I activity, indicating that the SDS/PAGE-purified prote...

The authors have analysed protein contents, protein fractions, free amino acid and total amino acid contents of the mother’s colostrum and mother’s milk in comparison with the newest publications. They have established that there was no united picture of the different effects on protein contents of the mother’s milk. Protein contents of the colostrum of well-nourished mothers were found 6.0%, w...

the reflectance spectrum of green leaves is considerably affected by their biochemical and biophysical properties. it is possible to extract biochemical information from a continuous vegetation spectrum produced using hyperspectral sensors. the numerous absorption features present in the vegetation spectrum carry a considerable amount of information related to the content and the structure of t...

Phosphorylcholine (PC) is a classical ligand of C-reactive protein (CRP), a clinically important acute phase protein. In search of new ligands, CRPs were affinity-purified from several pathological samples, which exhibited distinct molecular variants induced in different diseases. Both glycosylated and non-glycosylated CRPs showed calcium-independent differential-binding to Staphylococcus aureu...