نتایج جستجو برای: phototoxicity

تعداد نتایج: 859  

Journal: :Chemical communications 2015
Albert Gandioso Evyenia Shaili Anna Massaguer Gerard Artigas Alejandro González-Cantó Julie A Woods Peter J Sadler Vicente Marchán

A new anticancer agent based on the conjugation of a photoactivatable Pt(IV) pro-drug to a cyclic RGD-containing peptide is described. Upon visible light irradiation, phototoxicity was induced preferentially in SK-MEL-28 melanoma cancer cells overexpressing αVβ3 integrin compared to control DU-145 human prostate carcinoma cells.

2010
Charles Jackson Jelena Kovačević Frederick Lanni Robert F. Murphy Gustavo K. Rohde

This thesis presents a new acquisition framework that models fluorescence microscope data during acquisition, and uses these learned models to intelligently guide future acquisitions. This framework results in significant time savings, as well as in reducing the photobleaching and phototoxicity incurred during acquisition. Fluorescence microscopy is a popular tool for live-cell imaging, and in ...

2012
Robert J. Miller Samuel Bennett Arturo A. Keller Scott Pease Hunter S. Lenihan

Nanoparticulate titanium dioxide (TiO(2)) is highly photoactive, and its function as a photocatalyst drives much of the application demand for TiO(2). Because TiO(2) generates reactive oxygen species (ROS) when exposed to ultraviolet radiation (UVR), nanoparticulate TiO(2) has been used in antibacterial coatings and wastewater disinfection, and has been investigated as an anti-cancer agent. Oxi...

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