نتایج جستجو برای: peripheral dose distribution
تعداد نتایج: 1070220 فیلتر نتایج به سال:
AIMS AND BACKGROUND To calculate peripheral radiation dose to the second primary site in patients who have developed a second malignancy after breast cancer radiotherapy (index cases) and to compare it with dose in the analogous anatomical site in radiotherapy-treated breast cancer patients who did not experience a second malignancy (controls). To evaluate the feasibility of Peridose-software p...
introduction: occupational exposure to ionizing radiation due to medical activities (both diagnostic and therapeutic procedures) has increased sharply in recent years. among the occupationally exposed workers in these fields, those most affected by this increased exposure to ionizing radiation are nuclear medicine workers. in this study, annual average effective dose, annual collective effectiv...
The micronucleus assay in human peripheral blood lymphocytes is a sensitive indicator of radiation damage and could serve as a biological dosimeter in evaluating suspected overexposure to ionising radiation. Micronucleus (MN) frequency as a measure of chromosomal damage has also extensively been employed to quantify the effects of radiation dose rate on biological systems. Here we studied the e...
Background: Premature chromosome condensation (PCC) is a method for interphase chromosome analysis in biodosimetry. This study was performed to verify the usefulness of PCC induced by calyculin A in human peripheral blood lymphocytes (pbl) for biological dosimetry and possible construction of dose-response curve. Materials and Methods: Peripheral blood was obtained from a healthy donor and expo...
X-ray computed tomography is an imaging method which makes tomographic images with high contrast and resolution. However, CT-scans deliver much more radiation dose compared with other imaging techniques. The aim of this study was to evaluate two-dimensional dose distribution in a PMMA phantom as well as investigationof the effect ofcollimation factor on the dose distribution measuredusing GAF-C...
Chemotherapy-induced neuropathy is a common, dose-dependent adverse effect of several antineoplastics. It can lead to detrimental dose reductions and discontinuation of treatment, and severely affects the quality of life of cancer survivors. Clinically, chemotherapy-induced peripheral neuropathy presents as deficits in sensory, motor, and autonomic function which develop in a glove and stocking...
PURPOSE A phase I trial of BMS-214662, a selective farnesyltransferase inhibitor with significant preclinical antitumor activity in which drug was given as a weekly 1-hour infusion for four of six weeks, was conducted to evaluate the tolerability, pharmacokinetics, and pharmacodynamic effect on farnesyltransferase activity in peripheral blood mononuclear cells. EXPERIMENTAL DESIGN BMS-214662 ...
background: radiochromic film is used for radiation dose measurement, xr-rv3 is used in fluoroscopy and ebt2 film in radiation therapy. the aim was to determine if the dosimetric properties of these two films are comparable in megavolt photon beams. materials and methods: comparison measurements included: calibration curves, heterogeneous phantom dose profiles, and nasopharynx dose distributio...
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