Cellular senescence is a durable cell cycle arrest as result of the finite proliferative capacity cells. Senescence responds to both intrinsic and extrinsic cellular stresses, such aging, mitochondrial dysfunction, irradiation, chemotherapy. Here, we report on use mass cytometry (MC) analyze multiple model systems demonstrate MC platform for analysis at single-cell level. We changes p16 express...

Olah Bakat Siswa Aktif (OBASTIF)—a talent sport event for Madrasah Tsanawiyah level held at MA Miftahul Qulub Polagan Galis Pamekasan as a promotion strategy which in its implementation goes through stages namely planning, and evaluation. The study focuses on (1) How is the planning of OBASTIF (2) (3) result OBASTIF. This research uses qualitative approach with descriptive type. data were obtai...

Lebih dari 1 juta diperoleh setiap hari di seluruh dunia, Infeksi menular seksual adalah infeksi yang penularannya melalui hubungan seksual. Masih tingginya tahun angka Menular Seksual (IMS) termasuk pada remaja itu tidak terlepas gaya hidup didalamnya pengetahuan dan sikap mengenai (IMS).Penelitian ini bertujuan untuk mengetahui pengaruh media video leaflet terhadap tentang IMS SMA Negeri 2 Ta...

The aquifer of the alluvial terraces Béni Abbès palm grove is subject to a hyperarid climate. groundwater salinity problem caused by several human and natural factors, causing serious irrigation problems. Hydrochemical analyses over 40-year interval show an alarming Spatio-temporal evolution salinity: drying up Saoura valley due, on one hand, impact construction Djorf Torba dam, o...

Pediatric sarcoidosis comprises a spectrum of childhood granulomatous inflammatory conditions. Pathological hallmark of the disease is granuloma formation that is seen in the affected tissues and almost any organ or system can be involved. There are two forms of pediatric sarcoidosis. One is seen in older children and the clinical picture is very similar to that of adult sarcoidosis and the oth...

This paper contributes to existing debates on the significance of modem diasporas in the context of global politics. In particular, it examines how nationalism has adapted to the newly emerging transnational environment. The new type of nationalism, long-distance nationalism, utilises modern forms of communication and travel to sustain its potency and relevance. Long-distance nationalism is not...

ownload sion of apoptosis is a known feature of cancer cells. One mechanism of deregulating the apoptotic paththrough overexpression of antiapoptotic BCL2 family members. ABT-263 (navitoclax) is a first-in-class family inhibitor that restores the ability of cancer cells to undergo apoptosis. However, many cancer re resistant to ABT-263 due to high levels of a BCL2 family member, MCL1, which is ...